OBJECTIVES Our goal is to analyze the degree of concordance between the Gleason score (GS) obtained in prostate biopsies and the one after radical prostatectomy. The intention is to know whether 12-core biopsy, instead of 6 (sextant biopsy), improves, or not, this correlation. METHODS A Cohort/prevalence study was conducted on 128 patients who underwent prostate biopsy and subsequent radical ...

BACKGROUND ChromograninA in prostate carcinoma (PC) indicate NE differentiation. This tumour is more aggressive and resistant to hormone therapy. PATIENTS AND METHODS We analyzed the incidence of pre-operative ChromograninA serum levels in non metastatic PC patients. Serum PSA and ChromograninA were analyzed before treatment. Clinicopathological parameters were evaluated in relation to serum ...

BACKGROUND Prostate cancer is the most common malignant tumour in men and the second most common cause of male cancer death. The study examines the clinicopathological features of patients with prostate cancer consecutively diagnosed at a private Diagnostic Radiology Centre in Western Jamaica over a 6-year period. METHOD The medical records, including the pathology reports of 423 consecutive ...

BACKGROUND The Gleason histological score is an independent prognostic factor in prostate cancer that helps in therapeutic decisions. AIM To analyze the concordance between the Gleason score of needle prostatic biopsy and the score from the study of the surgical piece obtained during radical prostatectomy. MATERIAL AND METHODS Retrospective analysis of 212 cases of prostate cancer, diagnose...

The Gleason score is one of a number of factors used in staging patients diagnosed with prostate cancer and in determining the treatment path such patients will ultimately follow. However, discrepancies in the Gleason scores obtained through biopsy compared with the final pathological staging of specimens following radical prostatectomy are not uncommon. Incorrect Gleason scoring can potentiall...

The Gleason score is one of a number of factors used in staging patients diagnosed with prostate cancer and in determining the treatment path such patients will ultimately follow. However, discrepancies in the Gleason scores obtained through biopsy compared with the final pathological staging of specimens following radical prostatectomy are not uncommon. Incorrect Gleason scoring can potentiall...

We assessed the correlation between BMI and Gleason score in prostate biopsies in Chinese Population. In this retrospective study, we collected the Gleason score, PSA, BMI, age, race, and other related clinical data on 290 patients who had undergone prostatic biopsy. We then compared the prostate cancer detection rates and Gleason scores between the high BMI group (BMI ≥ 25; 143 cases) and low ...

It is still difficult to gauge the probability that a patient with low-risk prostate cancer may be upgraded to a higher prostate cancer stage. Upgrading, using the Gleason score after a biopsy, can occur in anywhere from 30% to 50% of prostate cancer cases. Low-risk disease is generally associated with low prostate-specific antigen (PSA) production and a Gleason score of 6 or lower. The Gleason...