Waldheimia glabra is traditionally used as incense and as an anti-influenza drug by Tibetans in China. Here, we collected W. glabra from the Gangs Rinpoche mountain at an altitude of 5200 m, and analyzed its essential oil by gas chromatography-mass spectrometry (GC-MS) combined with the retention indices (RI). Twenty-seven compounds, representing 72.4% of the total essential oil, were identifie...

Efficacyand safety of a new herbal cream containing aqueous extracts of Azadirachta indica, Curcuma longa, Pongamia glabra, Glycyrrihiza glabra and Santallum album were evaluated in amulticentric, randomized, double-blind, placebo-controlled study. With active drug treatment, there was significant improvement in various signs like redness, oedema and symptoms like itching, burning, discharge an...

conclusions this study showed that topical glycyrrhiza glabra appeared to be a promising alternative in the treatment of olp. further studies should be conducted to assess the long-term effects of glycyrrhiza glabra. objectives the aim of this study was to compare the efficacy and safety of 1% glycyrrhiza glabra in orabase with 0.1% triamcinolone acetonide paste in treating oral lichen planus (...

Isolation of CYP72A154, a gene involved in glycyrrhizin biosynthesis pathway, Glycyrrhiza glabra L. (Iranian licorice)

licorice is obtained from glycyrrhiza glabra (g. glabra) in iran. glycyrrhizin is the main constituent of g. glabra and has several pharmacological effects. it is hydrolyzed to glycyrrhetic acid (ga) in the intestine after oral administration. in this study, a novel hplc method was used to determine the concentration of ga in rat plasma after oral administration of licorice aqueous extract. the...

Primary dysmenorrhea is a common gynecological disorder in women of reproductive age. Despite the effective treatments such as nonsteroidal anti-inflammatory drugs and oral contraceptives, researchers have always been looking for alternative drugs due to the adverse effects and limited efficacy of conventional medications. Glycyrrhiza glabra L. (G. glabra), commonly known as Licorice, has been ...

Tuberculosis (TB) remains a highly significant infection of microbial origin causing death of human in developing countries. The anti-tubercular drugs are less effective because of the emergence of multi-drug resistant strains and ineffective to extensively drug resistant strains of Mycobacterium tuberculosis. Plants are being an alternative source of antimicrobial compounds; the aim of this st...

Sarcandra glabra was a renowned herb traditionally used as herbal tea or food supplement to enhance mental efficiency and to recover from stress or fatigue in China. We investigated the effects of Sarcandra glabra extract (SGE), with chemical composition clearly showed by HPLC fingerprint as quality control, on immunologic response including natural killer (NK) cell activity and its antioxidati...

The association of chronic inflammation with development of human cancer is well recognized. There are number of reports of involvement of inflammatory process in the initiation and progress of cancer. The search for selective inhibitors of Cyclooxygenase-2 isoenzymes and that too from natural origin is considerably important. Rubia cordifolia L. and Glycyrrhiza glabra L. find an important plac...