نتایج جستجو برای: girk2

تعداد نتایج: 157  

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2005
Lachlan Thompson Perrine Barraud Elin Andersson Deniz Kirik Anders Björklund

Transplants of fetal ventral mesencephalic tissue are known to contain a mixture of two major dopamine (DA) neuron types: the A9 neurons of the substantia nigra pars compacta (SNpc) and the A10 neurons of the ventral tegmental area (VTA). Previous studies have suggested that these two DA neuron types may differ in their growth characteristics, but, because of technical limitations, it has so fa...

2009
Daisuke Nishizawa Makoto Nagashima Ryoji Katoh Yasuo Satoh Megumi Tagami Shinya Kasai Yasukazu Ogai Wenhua Han Junko Hasegawa Naohito Shimoyama Ichiro Sora Masakazu Hayashida Kazutaka Ikeda

Opioids are commonly used as effective analgesics for the treatment of acute and chronic pain. However, considerable individual differences have been widely observed in sensitivity to opioid analgesics. We focused on a G-protein-activated inwardly rectifying potassium (GIRK) channel subunit, GIRK2, that is an important molecule in opioid transmission. In our initial polymorphism search, a total...

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