random early detection (red) is one of the most commonly used active queue management (aqm) algorithms that is recommended by ietf for deployment in the network. although red provides low average queuing delay and high throughput at the same time, but effectiveness of red is highly sensitive to the red parameters setting. as network condition varies largely, setting red's parameters with fixed ...

Existence of capacity drop phenomenon, as the difference between pre-queue and queue discharge flow rates, has been one of the controversial concepts of traffic engineering. Several researches have focused on capacity drop existence and also its estimation issues. This paper aims to estimate capacity drop based not only on a comparison between breakdown and queue discharge flow rates, but also ...

In this paper, a meta-heuristic method, the Bat Algorithm, based on the echolocation behavior of bats is used to determine the optimum service rate of a queue problem. A finite buffer M/M/1 queue with N policy, multiple working vacations and Bernoulli schedule vacation interruption is considered. Under the two customers' impatient situations, balking and reneging, the...

Concerns have been raised that a focus on greenhouse gas removals (GGR) in climate models, scientific literature and other media might deter measures to mitigate change through reduction of emissions at source – the phenomenon ‘mitigation deterrence’. Given urgent need for action, any delay would be worrying. We convened nine deliberative workshops expose stakeholders futures scenarios involvin...

This paper reports a study on a single server queue with bulk arrival and bulk service patterns wherein the incoming traffic depends on the state of the server which may be in operating or breakdown state. The repair of the breakdown server is performed in two phases. The operating duration of server, repair duration of both phases of repairing as well as job's inter-arrival times and service t...

Nucleotide excision repair (NER) is the major DNA repair process that removes diverse DNA lesions including UV-induced photoproducts. There are more than 20 proteins involved in NER. Among them, XPC is thought to be one of the first proteins to recognize DNA damage during global genomic repair (GGR), a sub-pathway of NER. In order to study the mechanism through which XPC participates in GGR, we...

Drivers in urban neighborhoods who patrol streets, seeking inexpensive on-street parking create a significant fraction of measured traffic congestion. The pool of drivers patrolling at any time can be modeled as a queue, where ‘queue service’ is the act of parking in a recently vacated parking space and queue discipline is SIRO – Service In Random Order. We develop a queueing model of such driv...

Waiting in long queue is undesirable due to which in some practical situations customers become impatient and leave the system. In such cases providing additional servers can reduce long queue. This investigation deals with multi-server queueing system with additional servers and discouragement. The customers arrive in poisson fashion and are served exponentially by a pool of permanent and addi...

Both the ERCC1-XPF complex and the proteins involved in homoIogous recombination (HR) have critical roles in inter-strand cross-link (ICL) repair. Here, we report that mitomycin C-induced lesions inhibit replication fork elongation. Furthermore, mitomycin C-induced DNA double-strand breaks (DSBs) are the result of the collapse of ICL-stalled replication forks. These are not formed through repli...