the objective of this study was to determine the prevalence and distribution of chlamydia trachomatisgenotypes in shiraz, iran. two hundred twelve cervical swab samples were collected from women attendingshahid motahari polyclinic in shiraz, iran. the endocervical specimens were screened for c. trachomatis byplasmid pcr. genotyping was performed in c. trachomatis-positive samples by nested pcr ...

AIM To investigate the HCV genotype distribution in Romania in the first national study, to establish the correlations with epidemiological, biochemical, virological and histological features and to compare our results with those from neighboring countries. PATIENTS AND METHODS Two distinct groups of patients and two methods were used: 153 patients in the frame of ACHIEVE study with genotypin...

BACKGROUND Distribution of Hepatitis C Virus (HCV) genotypes may be changed over time. Epidemiological Studies on distribution patterns of HCV genotypes in Pakistani population might assist for better treatment options and preventive strategies. OBJECTIVES This study was conducted to determine distribution patterns of HCV genotypes in different geographical regions of Pakistan. PATIENTS AND...

the cd1 family is less variable transmembrane antigen presenting molecules related to the mhc molecules. cd1a and cd1e genes are the most polymorphic ones associated with autoimmune diseases. the aim was to better clarify the map of cd1 genes in southwest iranian normal population for implications in vaccine design.in this study we investigated the polymorphism of cd1a, cd1d and cd1e in 311 hea...

This study used pyrosequencing to determine the proportional distribution of CYP3A5*3 genotypes to further confirm the homogeneous phenomenon that is observed when recipients and donors in living donor liver transplantation (LDLT) have a different single nucleotide polymorphism (SNP) genotype. We enrolled 42 recipient/living donor pairs and the SNPs of CYP3A5*3 were identified by polymerase cha...

beta-Mannosidosis is a lethal lysosomal storage disease inherited as an autosomal recessive in man, cattle and goats. Laboratory assay data of plasma beta-mannosidase activity represent a mixture of homozygous normal and carrier genotype distributions in a proportion determined by genotype frequency. A maximum likelihood approach employing data transformations for each genotype distribution and...

The purpose of this study was to determine the prevalence and distribution of HCV genotypes among voluntary blood donors in northern Thailand. From 1998 to 2000, 167 serum samples which tested positive for anti-HCV antibodies in the screening of voluntary blood donors from 5 provinces in northern Thailand were selected for genotyping. Viral RNA was extracted from the sera. The core-E1 region of...

conclusions the current study shows that the predominant hcv genotype among inmates from prison in potulice is genotype 3. results the most frequent hcv genotype among inmates was genotype 3, which was detected in169 of 281 patients (60.1%). most frequent genotype among hospitalized was genotype 1, which was found in 1127 cases (79.6%). comparing the results of prisoners with a group of patient...

AIM To explore the association between COX-2 polymorphisms and non-small cell lung cancer (NSCLC) susceptibility. METHODS We collected fasting peripheral venous blood from 60 cases with NSCLC and 62 healthy controls through physical examinations, and applied PCR-RFLP to analyze COX-2 polymorphisms of two groups. RESULTS With respect to detecting COX-2 rs689466 and rs5275 polymorphisms, the ...