نتایج جستجو برای: genotype 6

تعداد نتایج: 1037231  

Journal: :British journal of clinical pharmacology 1995
G P Todd I G Chadwick K S Higgins W W Yeo P R Jackson L E Ramsay

1. The effects of a single oral dose of enalapril 10 mg on serum ACE activity and blood pressure in relation to the ACE genotype were studied in 27 healthy men, n = 9 each of genotype DD, ID and II, in a parallel group study design. 2. Before treatment serum ACE activity differed significantly between the genotypes, with serum ACE activity 56% higher in DD than II subjects, and the genotype exp...

2016
Yan-Wei Zhong Hong-Fei Zhang Yan-Min Shi Yong-Li Li Fang Chu Zhi-Qiang Xu Da-Wei Chen Yu Gan Fu-Chuan Wang Mei-Lei Gu Yi Dong Shi-Shu Zhu Ce Shi Hua-Hao Fan Xiu-Chang Zhang Min Zhang

Clinical data on children with chronic hepatitis C (CHC) remain extremely limited. This study investigated sustained virologic response (SVR) to alfa-interferon 2b plus RBV treatment in children aged 1-6 years with unsafe injection-acquired CHC. 154 children with CHC aged 1 to 6 years were enrolled, 101 of them were male (65.6%) and 53 were female (34.4%), and they were treated with alfa-interf...

2017
Su Rin Shin Young Seok Kim Young-Seok Lim June Sung Lee Jin Woo Lee Sun Myung Kim Sook-Hyang Jeong Joo Hyun Sohn Myung Seok Lee Sang Hoon Park

Background/Aims Because of the limited geographic distribution, there have been insufficient data regarding hepatitis C virus (HCV) genotype 6 in Korea. This study aimed to investigate the clinical characteristics and available treatment outcomes of patients with genotype 6 HCV in Korea. Methods From 2004 to 2014, data were collected from Korean patients infected with genotype 6 HCV in eight ...

2014
Luís Belo Henrique Nascimento Michaela Kohlova Elsa Bronze-da-Rocha João Fernandes Elísio Costa Cristina Catarino Luísa Aires Helena Ferreira Mansilha Petronila Rocha-Pereira Alexandre Quintanilha Carla Rêgo Alice Santos-Silva

OBJECTIVES Bilirubin has potential antioxidant and anti-inflammatory properties. The UGT1A1*28 polymorphism (TA repeats in the promoter region) is a major determinant of bilirubin levels and recent evidence suggests that raised adiposity may also be a contributing factor. We aimed to study the interaction between UGT1A1 polymorphism, hematological and anthropometric variables with total bilirub...

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