People are exposed to an ever-increasing number of chemical compounds that are developed by industry for a wide range of applications. These compounds may harmfully react with different cellular components and activate specific defense mechanisms that provide protection against the toxic, mutagenic, and possibly oncogenic consequences of exposure. Monitoring the activation of specific cellular ...

Rubinstein–Taybi syndrome is a multisystem pathology characterized by mental retardation and delayed physical development in combination with set of phenotypic features, which make up recognizable pattern the disease. This review literature highlights molecular‑genetic basis presumed pathogenesis syndrome, considers questions geno‑phenotypic correlations differential diagnosis group pathologies...

W. A GENO,* M. CR OWT HER , T . BA GL I N , A. FALANGA,§ H . BULLER– and G . PA LARET I ** *Department of Clinical and Experimental Medicine, University of Insubria, Varese, Italy; McMaster University, Hamilton, Canada; Department of Hematology, University of Cambridge, Cambridge, UK; §Division of Immunohematology and Transfusion Medicine, Ospedali Riuniti di Bergamo, Bergamo, Italy; –Academic ...

Mycoplasma bovis pneumonia in cattle has been epidemic in China since 2008. To investigate M. bovis pathogenesis, we completed genome sequencing of strain HB0801 isolated from a lesioned bovine lung from Hubei, China. The genomic plasticity was determined by comparing HB0801 with M. bovis strain ATCC® 25523™/PG45 from cow mastitis milk, Chinese strain Hubei-1 from lesioned lung tissue, and 16 o...

Potato virus Y (PVY) as one of the serious diseases on tobacco (Nicotiana tabacum L.), reduces leaf yield and its quality. Use of re-sistant genotypes is being considered as the most effective, economical and a safe way to reduce damages of the virus. In the present study, the response of 90 oriental and semi-oriental tobacco genotypes was evaluated against PVY using randomized complete block d...

Biosphere Reserves attempt to align existing biodiversity conservation with sustainable resource use, specifically for improving socio-economic circumstances of resident communities. Typically, the Biosphere Reserve model is applied to an established landscape mosaic of existing land uses; these are often socio-ecological systems where strict environmental protection and community livelihoods a...