conclusions il6 and il8 gene polymorphisms have no role in nash pathogenesis and liver fibrosis process, but presence of the a/a genotype in the il8 gene is associated with disease progression. patients and methods consecutive patients with biopsy proven nash and age- and gender-matched healthy individuals with normal liver function tests and normal ultrasonography were enrolled in the study. h...

background: the goal of the present work was to determine frequencies of different finger patterns of a population in hamadan (one of the western cities of iran) in 1997. methods: in a cross-sectional study, the .prints of the first phalanx of both hands of 717 randomly selected hamadan students (i88 men, 529 women) have taken, by using standard method (stamp ink). the fingerprints were classif...

background:in the recent decade, the reverse genetics method has been broadly used for rescue of negative-stranded rna viruses from cdna or viral minigenomes. this technique has been applied to study different steps in virus replication and virus-host interactions. reverse genetics could also be implemented for design of new vaccines. the t7 rna polymerase activity as well as virus (nucleocapsi...

The theory of population genetics and evolutionary computation have been evolving separately for nearly 30 years. Many results have been independently obtained in both fields and many others are unique to its respective field. We aim to bridge this gap by developing a unifying framework for evolutionary processes that allows both evolutionary algorithms and population genetics models to be cast...

Ontogenetic sequences are a pervasive aspect of development and are used extensively by biologists for intra- and interspecific comparisons. A tacit assumption behind most such analyses is that sequence is largely invariant within a species. However, recent embryological and experimental work emphasizes that ontogenetic sequences can be variable and that sequence polymorphism may be far more pr...

Selection for reproduction in the context of Genetic Algorithms uses only one selection scheme to select parent individuals. When considering the model of sexual selection in the area of population genetics it gets obvious that the process of choosing mating partners in natural populations is different for male and female individuals. In this paper the authors introduce a new selection paradigm...

The general linear structural equation model is applied to problems in human genetics where there may be more than one measured phenotype per individual. A modeling convention, termed conditional associations, is developed to extend the general linear model so that it can handle the unique problems in human genetic models that arise from the pairing up of individuals or families under assortmen...