social anxiety disorder (sad) is the one of the most common anxiety disorders. despite its high prevalence, the disorder is still considerably undiagnosed and untreated. the disease places a massive burden on patient’s lives, affecting not only their social interactions but also their educational and professional activities, thereby constituting a severe disability. γ-aminobutyric acid (gaba) s...

social phobia is an anxiety disorder characterized by heightened fear and avoidance of one or more social or performance situations, including public speaking, meeting new people, eating or writing in front of others and attending social meetings. people with social phobia are typically anxious about the possibility that others will evaluate them negatively and/or notice symptoms of their anxie...

high comorbidity between psychological disorders causes attention to the mechanisms responsible for this comorbidity and common cognitive factors involved in these disorders. these are known as transdiagniostic factors. similarity evidence and high comorbidity between generalized anxiety disorder (gad) and obsessive compulsive disorder (ocd) introduce them as neighboring disorders. the purpose ...

Background: Major depressive disorder (MDD) and general anxiety (GAD) share many common features, leading to numerous challenges in their differential diagnosis. Given the importance of microbiota–gut–brain axis, we investigated differences gut microbiota between representative cases these two diseases sought develop a microbiome-based approach for Methods: We enrolled 23 patients with MDD, 21 ...

BACKGROUND Major depressive disorder (MDD) and anxiety disorders are common and result in considerable suffering and economic loss. People suffering from major depressive disorder and/or anxiety disorders are commonly encountered in the primary care setting. Unfortunately, most people with these disorders remain either untreated or inadequately treated; current data suggest that general practit...

BACKGROUND Little is known about seasonality of specific depressive symptoms and anxiety symptoms in different patient populations. This study aims to assess seasonal variation of depressive and anxiety symptoms in a primary care population and across participants who were classified in diagnostic groups 1) healthy controls 2) patients with a major depressive disorder, 3) patients with any anxi...

An increasing body of evidence suggests that anxiety is associated with the risk of coronary heart disease. Literature on the association between anxiety and stroke is scarce and inconsistent. Although 1 study found no association between generalized anxiety disorder and stroke, another study showed that the risk of stroke increased with increasing anxiety symptom score. Therefore, these findin...

The available empirical literature suggests that anger may be characteristic of posttraumatic stress disorder (PTSD). Meta-analytic strategies were used to evaluate the extent to which the experience of anger is specific to PTSD rather than anxiety disorders in general. Thirty-four anxiety disorder patient samples (n=2,169) from 28 separate studies were included in the analysis. Results yielded...

in this investigation, the effect of group cognitive-behavior therapy in reduction of anxiety and dysfunctional attitude were studied on patients with generalized anxiety disorder (gad). 20 female participants were recognized to have gad by the researcher through a clinical interview on the basis of dsm-iv-tr standards and invited to take part in the study. they first filled in the dysfunctiona...