نتایج جستجو برای: gem tv

تعداد نتایج: 20064  

Journal: :In vivo 2004
Genovefa D Kolovou Dimitri P Mikhailidis Nikolaos Kafaltis Evdokia N Adamopoulou Elefterios Yazitsoglou Aggeliki Hatzaki Nectarios Pilatis Alexandra P Margeli Klelia D Salpea Michael Mykoniatis Dennis V Cokkinos

INTRODUCTION The ingestion of alcohol (Alc) as well as gemfibrozil (Gem), a fibrate drug used to treat hypertriglyceridaemia, may occur on a long-term basis in humans. Since both Alc and Gem can disturb liver function, we assessed the effects of administering Alc together with Gem in Wistar rats. MATERIALS AND METHODS Male Wistar rats were randomized and divided into 4 groups of 10 each. They...

Journal: :Chemistry 2014
Bing Gao Yanchuan Zhao Mingyou Hu Chuanfa Ni Jinbo Hu

The direct conversion of diaryl ketones and enolizable aliphatic aldehydes into gem-difluoroalkenes has been a long-standing challenge in organofluorine chemistry. Herein, we report efficient strategies to tackle this problem by using difluoromethyl 2-pyridyl sulfone as a general gem-difluoroolefination reagent. The gem-difluoroolefination of diaryl ketones proceeds by acid-promoted Smiles rear...

Journal: :Vaccine 2006
Sandrine A L Audouy Maarten L van Roosmalen Jolanda Neef Rolf Kanninga Eduard Post Mariëlle van Deemter Heidi Metselaar Saskia van Selm George T Robillard Kees J Leenhouts Peter W M Hermans

The present work reports the use of non-living non-recombinant bacteria as a delivery system for mucosal vaccination. Antigens are bound to the cell-wall of pretreated Lactococcus lactis, designated as Gram-positive enhancer matrix (GEM), by means of a peptidoglycan binding domain. The influence of the GEM particles on the antigen-specific serum antibody response was studied. Following nasal im...

Journal: :Basic & clinical pharmacology & toxicology 2011
Marija Macan Paško Konjevoda Jasna Lovric Marijan Koprivanac Marta Kelava Nada Vrkic Vlasta Bradamante

There are diverse experimental data about the influence of gemfibrozil (GEM) on the production of hydrogen peroxide (H(2)O(2)) and antioxidant enzymes. We investigated the influence of GEM treatment on the production of malondialdehyde (MDA) level in tissues of normolipidaemic Wistar and Fisher rats which is an index of lipid peroxidation. Because serum paraoxonase 1 (PON1) is an important enzy...

Journal: :International journal of oncology 2011
Nobuaki Kurata Hayato Fujita Kenoki Ohuchida Kazuhiro Mizumoto Prawej Mahawithitwong Hiroshi Sakai Manabu Onimaru Tatsuya Manabe Takao Ohtsuka Masao Tanaka

Gemcitabine (GEM) is the standard treatment for advanced/metastatic pancreatic cancer. However, there is a substantial subset of patients in whom the efficacy of GEM, when used as a single agent, is inadequate. Recently, the 5-fluorouracil (5-FU) prodrugs capecitabine and S-1 have been used as an alternative, either alone or in combination with GEM. The aim of the present study was to investiga...

Journal: :Annals of oncology : official journal of the European Society for Medical Oncology 2003
E Bajetta S C Stani D De Candis N Zaffaroni N Zilembo D Cortinovis S Aglione L Mariani B Formisano P Bidoli

BACKGROUND To explore the activity and tolerability of gemcitabine (GEM) and carboplatin (CBDCA) in non-small-cell lung cancer (NSCLC) we tested four administration sequences on H460 NSCLC cells, and at the same time performed a randomized phase II trial using analogous schedules. PATIENTS AND METHODS GEM was given first in two in vitro sequences, and CBDCA first in the other two; interaction...

2013

IDENTITY Citation · Winters JC, Dmochowski RR, Goldman HB, Herndon CD, Kobashi KC, Kraus SR, Lemack GE, Nitti VW, Rovner ES, Wein AJ. Adult urodynamics: American Urological Association (AUA)/Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction (SUFU) guideline. Linthicum (MD): American Urological Association (AUA); 2012 Apr. 30 p. [119 references] Date Released · 2012 GEM ...

ژورنال: راهبرد فرهنگ 2017

امروزه در دنیای رسانه، سریال‌‌های‌ تلویزیونی یکی از ژانر‌های‌ محبوبی است که توجه مخاطبان زیادی را به خود جلب نموده است. در این میان سریال ماهواره‌ای «‌عمر گل لاله» که به زبان فارسی در کانال GEM TV پخش می‌‌شود یکی از مهم‌ترین سریال‌‌هایی است که ذهن و وقتِ بینندگان به‌ویژه قشر زنان را به خود مشغول نموده است. مسئله اصلی تحقیق حاضر آن است که زنان به‌مثابه مخاطبان اصلی این سریال، آن را چگونه رمزگشایی...

2008
R. B. Burston

Abstract. This paper considers gauge-invariant and covariant gravitational perturbations on arbitrary vacuum locally rotationally symmetric (LRS) class II space-times. Ultimately, we derive four decoupled equations governing four specific combinations of the gravito-electromagnetic (GEM) 2-tensor harmonic amplitudes. We use the gauge-invariant and covariant 1+1+2 formalism which Clarkson and Ba...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2017
Andrew Chancellor Anna S Tocheva Chris Cave-Ayland Liku Tezera Andrew White Juma'a R Al Dulayymi John S Bridgeman Ivo Tews Susan Wilson Nikolai M Lissin Marc Tebruegge Ben Marshall Sally Sharpe Tim Elliott Chris-Kriton Skylaris Jonathan W Essex Mark S Baird Stephan Gadola Paul Elkington Salah Mansour

Tuberculosis (TB), caused by Mycobacterium tuberculosis, remains a major human pandemic. Germline-encoded mycolyl lipid-reactive (GEM) T cells are donor-unrestricted and recognize CD1b-presented mycobacterial mycolates. However, the molecular requirements governing mycolate antigenicity for the GEM T cell receptor (TCR) remain poorly understood. Here, we demonstrate CD1b expression in TB granul...

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