conclusions pet/ct can provide diagnosis and more accurate staging, location of tumor with its capability in providing the anatomical and physiological information synchronizes. therefore pet/ct plays an important role in oncology. objectives in this paper, we evaluate application of pet/ct for improve oncologic imaging. methods the papers were searched in pubmed and scopus databases with the r...

Backround: Abnormal expression of CXC chemokine receptor 1 (CXCR1) has shown the ability to promote tumor angiogensis, invasion and metastasis in several cancers. The purpose of our curret study is to discover the clinical prognostic significance of CXCR1 in resectable gastric cancer. METHODS 330 gastric cancer patients who underwent R0 gastrectomy with standard D2 lymphadenectomy at Zhongsha...

For a long time, surgery alone used to be the standard treatment for curable advanced gastric cancer. However, times have changed. Although different schedules and opinions exist between continents and countries, (neo)adjuvant treatment with chemotherapy and/or radiotherapy have been shown to improve survival outcome and are now also considered as standard. The optimal regimens are continuously...

background: e-cadherin is a calcium-dependent molecule that contributes to intercellular adhesion. its proper functioning is important in the maintenance of epithelial structure and integrity. e-cadherin serves as a very important tumor suppressor. in this study, we aimâ to determineâ the frequencyâ of e-cadherin expression aberrancy and its relationship to theâ biologicalâ behavior of gastric ...

Esophageal cancer is one of the most lethal of all neoplasms. During the last two decades, there have been significant changes in the epidemiology and treatment of esophageal cancer. The incidence of adenocarcinoma is increasing whereas that of squamous cancer is decreasing. Surgery, the mainstay of treatment of esophageal cancer, has been used with neoadjuvant chemoradiotherapy to improve prog...

Gastric cancer with pregnancy is rare and usually presents in late and advanced stage. Standard interventions in diagnosing, staging and treatment of cancer may be harmful for the fetus. The treatment of cancer in pregnancy should not differ significantly from the treatment in nonpregnant women. There have been case reports of open gastrectomy for gastric cancer in pregnancy. We present a case ...

Gastric cancer remains a considerable health burden throughout the world. The Cancer Genome Atlas (TCGA) analysis has recently unveiled 4 genotypes of gastric cancer with data not ready to change treatment strategy yet. A multimodality approach to therapy is the cornerstone of screening, diagnosing, staging, treating and supporting patients with gastric cancer. The evidence-based approach to lo...

We report the first case of early gastric cancer just above a heterotopic pancreas for which the differential diagnosis was carcinoma arising from heterotopic pancreas. Routine upper gastrointestinal endoscopy in an 83-year-old man with sigmoid colon cancer revealed a gastric cancer in the lesser curvature of the antrum. Endoscopic ultrasonography (EUS) for evaluating the depth of tumor invasio...

Although the overall incidence of gastric cancer has steadily declined in the United States, it is estimated that more than 12,000 persons died from gastric cancer in 2003. The incidence of distal stomach tumors has greatly declined, but reported cases of proximal gastric carcinomas, including tumors at the gastroesophageal junction, have increased. Early diagnosis of gastric cancer is difficul...

Gastric cancer is one of the most common tumors and the second leading cause of cancer mortality in the world (Kamangar et al., 2006) . In China, it is the leading cause of morbidity and mortality of neoplasm in digestive system. Until now, clinical surgery is the mainstay of gastric cancer treatment and only can cure parts of patients in the early-stage, but for the patients in the advanced st...