Frizzled (Fz) signaling regulates the establishment of planar cell polarity (PCP). The PCP genes prickle (pk) and strabismus (stbm) are thought to antagonize Fz signaling. We show that they act in the same cell, R4, adjacent to that in which the Fz/PCP pathway is required in the Drosophila eye. We demonstrate that Stbm and Pk interact physically and that Stbm recruits Pk to the cell membrane. T...

Planar cell polarity (PCP) is a common feature in many epithelia, reflected in cellular organization within the plane of an epithelium. In the Drosophila eye, Frizzled (Fz)/PCP signaling induces cell-fate specification of the R3/R4 photoreceptors through regulation of Notch activation in R4. Except for Dl upregulation in R3, the mechanism of how Fz/PCP signaling regulates Notch in this context ...

THE ROLE OF FRIZZLED-1 AND FRIZZLED-3 IN OLFACTORY SENSORY NEURONAL TARGETING. Mina G. Safain. Department of Neurosurgery, Yale University School of Medicine, New Haven, CT. While most areas of the brain do not exhibit profound neurogenesis or continuing synaptogenesis in the adult, there are notable exceptions which include the olfactory and hippocampal regions of the nervous system. In the ol...

BACKGROUND In this study, the international affective picture system was used to evoke emotion, and then the corresponding signals were collected. The features from different points of brainwaves, frequency, and entropy were used to identify normal, moderately, and markedly ill schizophrenic patients. METHODS The signals were collected and preprocessed. Then, the signals were separated accord...

Wheat is among the world’s most important agricultural crops, with winter wheat accounting for approximately 25.5% of total crop in Lithuania. The unchangeable goal production to achieve good and economically beneficial yield, but such efforts are often based on conventional agrotechnological solutions, excessive fertilization, which uneconomical negatively affects soil, environment, human heal...

We consider uid models with innnite buuer size. Let fZ N (t)g be the net input rate to the buuer where fZ N (t)g is a superposition of N homogeneous alternating on-oo ows. Under heavy traac environment fZ N (t)g converges in distribution to a centered Gaussian process with covariance function of a single ow. The aim of this paper is to prove the convergence of the stationary buuer content proce...

This study aimed to determine the relationship of some metabolic constituents in follicular fluid (FF) with size (FZ) and oocyte diameter (OD) local ewes ovaries (Ovis aries), from September 2021 February 2022 Laboratories Animal Production Department, Al-Musaib Technical College. Two hundred non-pregnant genital organs were collected abattoirs Babylon province carried laboratory within two hou...

This is the second of three lectures on introduction to vertex operator algebras. In this lecture, we shall continue Professor Dong’s lecture to present more fundamental properties of vertex operator algebras. From the mathematical point of view, a vertex operator algebra formally resembles a Lie algebra because the Jacobi identity is used as one of the main axioms. For the Lie algebra aspect o...

Fractures of the zygomatic complex and their treatment have been the focus of much attention in the last 30 years. Treatment frequently depends on the surgical findings, experience, and discretion of the surgeon. Treatment of zygomatic complex (ZMC) fractures often requires stabilization at the frontozygomatic (FZ) suture. Frodel’ and Marentette’ have described the use of lag screw fixation of ...

Fig 2: A selected slice showing the SWI (A,B) and MIP (C, D) images with FH and FZ filters (α = 3, β = -0.1). Compared to FH (left), the FZ (right) showed clear improvement in the tissue contrast, both between gray and white matter tissue (B vs. A) and between veins and surrounding tissues (D vs. C). Fig 3: Determination of the optimal parameters α and β for FZ, using CoM. The optimal α is 2 t...