xiv

There are currently no experiments, either satellite or ground-based, that are sensitive to astro-physical γ-rays in the energy range between 20 and 250 GeV. We are developing the Solar Tower Atmospheric Cherenkov Effect Experiment (STACEE) to explore this energy range. STACEE will use heliostat mirrors at a solar research facility to collect Cherenkov light in extensive air showers produced by...

squamous cell carcinoma of the gallbladder is rare and constitutes only 0.5-3% of all malignancies of this organ. most of the reported cases have had a component of adenocarcinoma. we report a 70-year-old man who presented with acute onset right upper quadrant pain. he operated on based on a presumptive diagnosis of acute cholecystitis according to clinical and ultrasonographic findings. histop...

telomerase and systems controlling their activity have been of great attention. there are controversies regarding the role of the alternative splicing forms of the human telomerase reverse transcriptase (htert), the catalytic subunit of telomerase. therefore, the correlation between telomerase enzyme activity, the abundance of alternatively spliced variants of htert and doubling time of a serie...

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Cancer immunotherapy (passive or active) involves treatments which promote the ability of the immune system to fight tumor cells. Several types of immunotherapeutic agents, such as monoclonal antibodies, immune checkpoint inhibitors, non-specific immunomodulatory agents, and cancer vaccines are currently under intensive investigation in preclinical and clinical trials. Cancer vaccines induce pe...