Transcripts and protein for follicle-stimulating hormone receptor (FSHR) were demonstrated in abdominal adipose tissue of female chickens. There was no expression of the Fsh gene, but FSH and FSHR colocalized, suggesting that FSH was receptor bound. Partial correlations indicted that changes in abdominal fat (AF) content were most directly correlated with Fshr mRNA expression, and the latter wa...

It is currently admitted that Follicle-Stimulating Hormone (FSH) is physiologically involved in the development and function of fetal/neonatal Sertoli cells in the rat but not the mouse. However, FSH is produced by both species from late fetal life onwards. We thus reinvestigated the role of FSH in mouse testis development at day 0 (birth) 6, 8 and 10 post-partum (dpp) by using mice that lack f...

We previously reported that human follicular fluid contained a protein that inhibits binding of 125I-human FSH to its membrane receptor (FSH-BI) and demonstrates FSH-like agonist activity in vitro. The cellular origin of FSH-BI was unknown, although ovarian granulosa cells seemed a likely source. To address this question, human granulosa cells were collected from patients during routine in-vitr...

BACKGROUND When stimulating a patient with poor ovarian response for IVF, the maximal dose of gonadotropins injected is often determined by arbitrary standards rather than a measured response. The purpose of this study was to determine if serum FSH concentration during an IVF stimulation cycle reflects follicular utilization of FSH and whether serum FSH values may inform dose adjustments of exo...

Follicle-stimulating hormone (FSH) in the organism together with LH is responsible for follicular growth and maturation of eggs. If the ovaries are not working, FSH levels rise. The most common reason for high serum FSH concentration is in a female who is undergoing or has recently undergone menopause. High levels of follicle-stimulating hormone indicate that the normal restricting feedback fro...

Cultured rat ovarian granulosa cells respond to follicle-stimulating hormone (FSH) by synthesizing and secreting plasminogen activator. The specificity of the response for FSH prompted us to explore the use of this system as an in vitro bioassay for FSH. The release of FSH by pituitary cell cultures has been examined by this method, as have been preparations of FSH of known biological activity....

Citation: Younis JS (2017) Commentary: Efficacy of Follicle-Stimulating Hormone (FSH) Alone, FSH + Luteinizing Hormone, Human Menopausal Gonadotropin or FSH + Human Chorionic Gonadotropin on Assisted Reproductive Technology Outcomes in the “Personalized” Medicine Era: A Meta-analysis. Front. Endocrinol. 8:264. doi: 10.3389/fendo.2017.00264 Commentary: efficacy of FollicleStimulating Hormone (FS...

Human epidermal growth factor receptor 2 (HER2) is a transmembrane tyrosine kinase protein, Positive HER2 status has been linked with aggressive tumor behavior and resistance to cytotoxic endocrine therapies. Breast cancer complex disease the major cause of mortality in women worldwide. There are several subtypes breast many options for treatment. This study aimed know hormonal changes associat...