The delta9-tetrahydrocannabinol (delta9-THC) content was identified and determined quantitatively using a Gas Chromatography Detector (Gas Chromatography-Electron Ion Detector) instrument in samples of illicit herbal cannabis. Law enforcement authorities sent the samples to the Department of Forensic Medicine and Toxicology, University of Athens, for toxicological analysis. The concentrations o...

OBJECTIVE Benzodiazepines are frequently screened drugs in emergency toxicology, drugs of abuse testing, and in forensic cases. As the variations of benzodiazepines concentrations in biological samples during bleeding, postmortem changes, and redistribution could be biasing forensic medicine examinations, hence selecting a suitable sample and a validated accurate method is essential for the qua...

1 Department of Forensic Medicine and Veterinary Toxicology, Faculty of Veterinary Medicine, South Valley University, 83523 Qena-Egypt 2 Department of Medical Laboratories, Collage of Applied Medical Sciences, Majmaah University-Kingdom of Saudi Arabia 3 Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Hacettepe University, Sıhyyie/Ankara-Türkiye 4 Division of Cerebral Circuitry, N...

Pharmacogenetic and Pharmacogenomics are the study of association between an individual's genotype their response to xenobiotics Pharmacokinetic pharmacodynamics variations can appear at level drug-metabolizing enzymes, drug transporters, targets or other biomarker genes. can, therefore, be relevant in forensic toxicology. This review presents aspects together with some examples from daily rout...

From the Department of Forensic Medicine, Kasturba Medical College, Mangalore, India Received: Nov. 11, 2014; Accepted: Jan. 13, 2015 Correspondence to: Dr. Tanuj Kanchan, Department of Forensic Medicine and Toxicology, Kasturba Medical College, Mangalore, Manipal University, India. State Highway 65, Madhav Nagar, Manipal, India. Tel.: 91‐9448252394; Fax: 91‐824‐2428183; E‐mail: tanuj.kanchan@ ...

The toxicology community should be aware that pharmaceutical companies are developing deuterated analogues of therapeutic agents, purported to have improved margins of safety and reduced potential for drug interactions, according to a recent report (1). According to the article in Nature, companies are " snapping up intellectual property rights " on many of the modified drugs. Earlier this year...

Forensic toxicology is a highly specialized area of forensic science which requires expertise in analytical chemistry, pharmacology, biochemistry, and forensic investigation. The practicing forensic toxicologist is concerned not only with the isolation and identification of drugs and other pOlsons from tissues, but also with the interpretation of his findings for the medical examiner, coroner, ...

There is no greater analytical challenge in forensic toxicology than the “general unknown,” the search for drugs or poisons that might have caused a death, impaired a driver or drugged the victim of sexual assault. Typically, the first step in such an analysis is one or more screening procedures, each designed to detect a number of analytes in a single analytical pass. All else being equal, the...