BACKGROUND Anaphylaxis is a potentially fatal condition requiring immediate resuscitation. Data regarding the epidemiology of anaphylaxis are limited and inconsistent. A reason for the variability was unavailability of a universally acceptable case definition till 2005. We reviewed cases using this new definition AIM To review the incidence, clinical presentation, cause and outcome of anaphyl...

We present a user-friendly visual representation of The National Institute of Allergy and Infectious Disease and the Food Allergy and Anaphylaxis Network criteria so as to enhance recognition of anaphylaxis and active teaching and learning.

Background Anaphylaxis is a potentially life threatening allergic reaction. Failure to identify the inciting allergen places patients at risk of future life-threatening allergen exposure. Anaphylaxis guidelines recommend that all patients who experience anaphylaxis from an allergen encountered in a non-medical setting carry self injectable epinephrine and follow up with an allergist. Very littl...

Background In food dependent exercise-induced anaphylaxis, a food challenge followed by an exercise test, being the gold standard for diagnosis, might not be feasible under certain circumstances. Therefore, in vitro diagnostic tests can be helpful to clarify severe forms of exercise-related hypersensitivity syndromes. We report two patients with food allergy to non-specific LTPs presenting as e...

BACKGROUND Little is known about the frequency of and the features associated with recurrent anaphylaxis in pediatric populations. During 1994 to 1996, we enrolled 76 children affected by anaphylaxis in a prospective study to analyze their clinical and allergic features. OBJECTIVE To undertake a follow-up study of these children to ascertain how many experienced a recurrence of anaphylaxis. ...

BACKGROUND Oral food challenges are the clinical standard for diagnosis of food allergy. Little data exist on predictors of oral challenge failure and reaction severity. METHODS A retrospective chart review was done on all pediatric patients who had oral food challenges in a tertiary care pediatric allergy clinic from 2008 to 2010. RESULTS 313 oral challenges were performed, of which the ma...

Results Among the 1315 reported cases of anaphylaxis, 541 could be classified as food anaphylaxis, with level 1 (38%), level 2 (59%), and level 3 (3%) of probability. 212 patients were children (< 18yrs, age 7.4±5.4 yrs, M/ F=2.0), and 329 were adults (age 35.5±12.9 yrs, M/F= 0.5). The main implicated food allergens were nuts (31%), egg (16%), milk (15%), fish (8%) and sesame (7%) in children a...

Serious tick-induced allergies comprise mammalian meat allergy following tick bites and tick anaphylaxis. Mammalian meat allergy is an emergent allergy, increasingly prevalent in tick-endemic areas of Australia and the United States, occurring worldwide where ticks are endemic. Sensitisation to galactose-α-1,3-galactose (α-Gal) has been shown to be the mechanism of allergic reaction in mammalia...

Background As adolescents transition away from the comforts of their homes and parental guidance and into a more independent and changing lifestyle, those who are food allergic also become part of a high at-risk population for severe anaphylaxis. Many fatal and near fatal anaphylaxis due to foods occur in young adults and teens and this age group has a great need for food allergy education as t...

Foods are recognized as a common cause of urticaria; however, the role of food is considered to be more important in acute not chronic urticaria. Wheat is a basic ingredient found in many common foods. Food allergy to wheat is primarily described in children in the form of atopic dermatitis. It is rare in adults; where it is mainly reported in exercise-induced anaphylaxis. We report a case of w...