The Drosophila wing imaginal disc is subdivided into notum, hinge and blade territories during the third larval instar by formation of several deep apical folds. The molecular mechanisms of these subdivisions and the subsequent initiation of morphogenic processes during metamorphosis are poorly understood. Here, we demonstrate that the Dorsocross (Doc) T-box genes promote the progression of epi...

In the fold recognition approach to structure prediction, a sequence is tested for compatibility with an already known fold. For membrane proteins, however, few folds have been determined experimentally. Here the feasibility of computing the vast majority of likely membrane protein folds is tested. The results indicate that conformation space can be effectively sampled for small numbers of heli...

Specialised literature presents a number of models describing the function of the vocal folds. In most of those models an emphasis is placed on the effect of Bernoulli’s air underpressure during the air passage through the glottis. The author defines a principle of the vocal folds function with a working version name „principle of the compressed air bubble“. The paper deals with the experimenta...