نتایج جستجو برای: floating drug delivery systems

تعداد نتایج: 1874819  

Journal: :Journal of Drug Delivery and Therapeutics 2012

Journal: :the iranian journal of pharmaceutical research 0
girish tripathi industrial pharmaceutic laboratory, saroj institute of technology and management lucknow-226001, india. satyawan singh industrial pharmaceutic laboratory, saroj institute of technology and management lucknow-226001, india. gopal nath department of microbiology and infectious disease, banaras hindu university varanasi, india.

oral ph sensitive drug delivery systems are of utmost importance as these systems deliver the drug at specific part of the gastrointestine (gi) as per the ph of gi, resulting in improved patient therapeutic efficacy and compliance. the ph range of fluids in various segments of the gi tract may provide environmental stimuli for drug release. the aim of this study was to design buoyant beads cont...

Journal: :Acta pharmaceutica 2016
Venkata Srikanth Meka Chew Ee Li Ravi Sheshala

The aim of this research was to formulate effervescent floating drug delivery systems of theophylline using different release retarding polymers such as ethyl cellulose, Eudragit® L100, xanthan gum and polyethylene oxide (PEO) N12K. Sodium bicarbonate was used as a gas generating agent. Direct compression was used to formulate floating tablets and the tablets were evaluated for their physicoche...

Girish Tripathi, Gopal Nath Satyawan Singh

   Oral pH sensitive drug delivery systems are of utmost importance as these systems deliver the drug at specific part of the gastrointestine (GI) as per the pH of GI, resulting in improved patient therapeutic efficacy and compliance. The pH range of fluids in various segments of the GI tract may provide environmental stimuli for drug release. The aim of this study was to design buoyant beads c...

Journal: :iranian journal of pharmaceutical sciences 0
monica rao aissms college of pharmacy, kennedy road, near r.t.o., pune, 411 001, india gajanan parikh aissms college of pharmacy, kennedy road, near r.t.o., pune, 411 001, india sameer borate aissms college of pharmacy, kennedy road, near r.t.o., pune, 411 001, india anuradha ranpise aissms college of pharmacy, kennedy road, near r.t.o., pune, 411 001, india yogesh mandage aissms college of pharmacy, kennedy road, near r.t.o., pune, 411 001, india kaushik thanki aissms college of pharmacy, kennedy road, near r.t.o., pune, 411 001, india

the objective of present research was to design, evaluate and compare drug release from two different dosage forms in pulsatile drug delivery system (dds) for metoprolol tartarate (mt) as tablet and capsule. pulsatile systems are gaining a lot of interest as they deliver the drug at the right site of action at the right time and in the right amount, thus providing spatial and temporal delivery ...

2015
Hai-feng Cheng Yan Feng Qun-jun Duan Da-Ming Jiang Kai-Yu Tao

Purpose: To formulate and evaluate floating microparticulate oral diltiazem delivery system for possible delivery to the heart. Method: Floating microspheres were prepared using cellulose acetate and Eudragit RS100 polymers by emulsion solvent evaporation technique. The dried floating microspheres were evaluated for micromeritic properties (flow properties, density, particle size determination)...

Journal: :Acta pharmaceutica 2010
Suresh Bandari Chandra Mohan Eaga Ashok Thadishetty Madhusudan Rao Yamsani

A biphasic gastroretentive drug delivery system of fenoverine was developed to maintain constant plasma concentration. The delivery system consisted of a loading-dose tablet and a floating multiple matrix tablet prepared by the direct compression process. The drug release from biphasic GRDDS in 0.1 mol L(-1) HCl and SGF (enzyme free) was sustained over 12 h with buoyant properties. Stability st...

2016
SUMIT DURGAPAL SAYANTAN MUKHOPADHYAY LAXMI GOSWAMI

Objective: The main purpose of this study is to prepare a floating micro articulated drug delivery system of ciprofloxacin by using non-aqueous solvent evaporation technique to increase the bioavailability and therapeutic effectiveness of the drug by prolonging its gastric residence time. Methods: Floating microparticles were prepared by using different low-density polymers such as ethyl cellul...

Journal: :Acta pharmaceutica 2008
Shailesh T Prajapati Laxmanbhai D Patel Dasharath M Patel

The purpose of the present study was to develop an optimized gastric floating drug delivery system (GFDDS) containing domperidone as a model drug. Box-Behnken design was employed in formulating the GFDDS with three polymers: hydroxypropyl methylcellulose K4M (HPMC K4M) (X1), Carbopol 934P (X2) and sodium alginate (X3), as independent variables. Floating lag time (FLT), total floating time (TFT)...

Journal: Current Medical Mycology 2018

Skin is an important organ of the body due to offering an accessible and convenient site for drug administration. One of the disadvantages of transdermal drug delivery is the low penetration rate of drugs through the skin. Over the past decades, nanoparticles have been used as drug delivery systems to increase therapeutic effects or reduce toxicity. Encapsulation of drugs in nanoparticulate ves...

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