CASE REPORT We present a case of ocular loiasis with a subconjunctival filaria, 5.5cm long, and a severe microfilaremia, 1 microfilaria/ml, on a previously asymptomatic woman from Equatorial Guinea, with a past medical history of hypereosinophilia of unknown origin. DISCUSSION Ocular loiasis is an imported infestation with a very low rate in our country. Nevertheless, chronic infestation in i...

Th? main object of this paper is to put before the readers: (1) the various points of interest with regard to the life-history, pathogenicity of filaria bancrofti, and the etiology of elephantiasis, lymphangitis, etc., (2) the several problems, so far solved, and those yet to be solved, in connection with the above, (3) to discuss certain features that are peculiar to filarial diseases, and als...

Tropical pulmonary eosinophilia (TPE) is a severe asthmatic syndrome of lymphatic filariasis, in which an allergic response is induced to microfilariae (Mf) in the lungs. Previously, in a murine model for TPE, we have demonstrated that recombinant interleukin-12 (IL-12) suppresses pulmonary eosinophilia and airway hyperresponsiveness (AHR) by modulating the T helper (Th) response in the lungs f...

Sheep intelectin1 and sheep intelectin3 (sITLN1 and sITLN3) were cloned and sequenced. The amino acid sequences of sITLN1 and sITLN3 shared 86% and 91% homology with the previously cloned sheep intelectin2 (sITLN2), respectively. Expression of sITLN1 and sITLN3 transcript was demonstrated in abomasum, lung, colon and gastric lymph node, terminal rectum, skin, jejunum, mesenteric lymph node, ile...

In several filarial genera the first stage larvae (microfilariae) are enclosed by an eggshell-derived sheath that provides a major interface between the parasite and the host immune system. Analysis of the polypeptide constituents of the microfilarial sheath from the cotton rat filaria Litomosoides sigmodontis identified two abundant surface glycoproteins: Shp3a and Shp3. The corresponding gene...

Dear Editor, Filaria is a common problem in India. The infection is seen endemically in the coastal regions especially around Orissa and Bihar. 1 Incidental filariasis has previously been described in cytology smears from a wide variety of sites 1 and its presence in a bone mar aspirate was described as early as 1976. association with hematologic malignancies is limited to only an occasional ca...