BACKGROUND Fibromyalgia is a chronic health condition characterized by widespread musculoskeletal pain, multiple tender points on physical examination, generalized muscular aching, stiffness, fatigue, nonrestorative sleep pattern, cognitive dysfunction, and mood disturbance. Recently, the Outcome Measures in Rheumatoid Arthritis Clinical Trials (OMERACT) Fibromyalgia Syndrome Workshop ranked an...

INTRODUCTION Fibromyalgia is a chronic pain syndrome with unknown etiology. Recent studies have shown some evidence demonstrating that oxidative stress may have a role in the pathophysiology of fibromyalgia. However, it is still not clear whether oxidative stress is the cause or the effect of the abnormalities documented in fibromyalgia. Furthermore, the role of mitochondria in the redox imbala...

BACKGROUND Fibromyalgia has been association with physical performance limitations. Additionally, activities of daily living have been reported to be directly associated with the exacerbation of pain and perceived exertion in this patient population. OBJECTIVES To compare the performance of a 6-minute walk (6MWT) test in patients with fibromyalgia and controls and to evaluate the relationship...

Background: The aim of the study is to find incidence fibromyalgia in orthopaedic female outpatient department a medical college hospital
 Methods: Cross-sectional conducted on patients coming orthopedic department.
 Results: result showed that about 42.00% diagnosed with syndrome (FMS). age group majorly affected by between 40-60 years age. Married women accounts major 89%
 Conc...

OBJECTIVE As smoking impacts physiological pathways in the central nervous system, it is important to consider the association between smoking and fibromyalgia, a pain condition caused predominantly by central nervous system dysfunction. The objectives were to assess the prevalence of current smoking among treatment-seeking chronic pain patients with (FM+) and without (FM-) a fibromyalgia-like ...

Fibromyalgia is a complex chronic condition characterized by pain, physical fatigue, sleep disorder and cognitive impairment. Evidence-based guidelines recommend antidepressants as treatments of fibromyalgia where tricyclics are often considered to have the greatest efficacy, with amitriptyline often being a first-line treatment. Amitriptyline evokes a preferential reduction in pain and fatigue...

OBJECTIVE The aim of this study is to evaluate the expression of Peripheral Benzodiazepine Receptors (PBRs) on leukocytes in patients affected by primary fibromyalgia and to argue their possible role in pain perception and in modulation of immunologic process. METHODS The expression of PBRs has been evaluated by flow cytometry on monocytes, on lymphocytes and on granulocytes in twenty patient...

Aims: Patients with fibromyalgia have very limited psychological flexibility that can lead to severe pain, depression, and other psychiatric disorders. The aim of this study was to investigate the effect of acceptance and commitment-based therapy on depression, chronic fatigue and pain intensity in patients with fibromyalgia with the effect of waiting and quarterly follow-up. Methods & materia...

OBJECTIVE To investigate whether fibromyalgia induces axonal damage in the optic nerve that can be detected using optical coherence tomography (OCT), as the retinal nerve fiber layer (RNFL) is atrophied in patients with fibromyalgia compared with controls. METHODS Fibromyalgia patients (n = 116) and age-matched healthy controls (n = 144) were included in this observational and prospective coh...