Although there is little doubt that more than one proteolytic enzyme occurs in plasma, plasmin (fibrinolysin) is the only such enzyme which has been definitely identified. Astrup and Permin,12 on the basis of differences in susceptibility to activation by streptokinase and fibrinokinase, have suggested that there are two precursors of fibrinolytic enzymes in human blood. They have designated th...

A new staphylococcal phage, Pphi-2, which could convert the capability of producing staphylokinase, was isolated. The phage is different from the phage reported by Winkler and co-workers [Nature(London) 195:407-408, 1962; J. Gen. Microbiol. 39:321-333, 1965]. The former is a single-converting phage belonging to serotype B, but the latter is a serotype F phage capable of converting not only stap...

By SAui I. COHEN A RECENT REPORT1 from this laboratory describes increases in certain of the tinbound amino acids and the appearance of a peptide after recalcification and subsequent coagulation of human blood plasma. It has been suggested2 that activation of plasminogen ( profibrinolysin ), the inactive enzyme precursor of the blood protease plasmin ( fibrinolysin ) , is accelerated during the...

Rhinoplasty is one of the most common aesthetic procedures in the world. It is the most common aesthetic surgery procedure in Iran. Achieving complete patient satisfaction is almost impossible but improving the aesthetics and function of the nose is the aim of surgery. This report describes a 34 years old woman with a large bump in the tip of the nose after three times cosmetic rhinoplasties. T...

ECENT YEARS have brought increased appreciation of the importance of the role of fibrinolysis in the regulation of normal hemostasis and in the production of abnormal bleeding. The mechanisms by which active fibrinolysis is induced are far from clear, but it does seem likely that it can be brought about by shock,1 severe emotional stress,2 injection of adrenalin,2 anoxia3 and liberation of acti...