نتایج جستجو برای: fev1
تعداد نتایج: 8085 فیلتر نتایج به سال:
Abstract Funding Acknowledgements Type of funding sources: Private grant(s) and/or Sponsorship. Main source(s): Stiftung KinderHerz Weserstr. 101 45136 Essen. Background For the last decades, surgical progress lead to better functional outcomes in patients with congenital heart defect (CHD), which may also affect lung function. Reduced volumes were found about half all a CHD. Purpose This prosp...
Airway obstruction is a relative contraindication to diving. Dive candidates are assessed clinically, and lung function tests evaluate variables such as forced vital capacity (FVC), forced expiratory volume in one second (FEV1) and the FEV1/FVC ratio. A small number of individuals have a normal FEV1, but a disproportionately large lung capacity, or pulmonary dysanapsis. These individuals have a...
Obstructive airways diseases typically present with dyspnoea, cough and wheeze, and are defined by a reduced forced expiratory volume in one second (FEV1/forced vital capacity (FVC) ratio. Traditionally, however, the severity of chronic obstructive pulmonary disease is graded by the FEV1 % predicted rather than the FEV1/FVC ratio, whilst other potentially valid measures of FEV1 impairment, such...
BACKGROUND Chronic obstructive pulmonary disease (COPD) is thought to result from an accelerated decline in forced expiratory volume in 1 second (FEV1) over time. Yet it is possible that a normal decline in FEV1 could also lead to COPD in persons whose maximally attained FEV1 is less than population norms. METHODS We stratified participants in three independent cohorts (the Framingham Offspri...
There is an increasing awareness that also growth in FEV1 may be of importance to development of chronic obstructive lung disease in later life. This paper reviews current knowledge on factors in foetal and childhood life that may reduce lung growth. Passive smoking as well as malnutrition in foetal life is related to impaired lung function in later life. Birth weight is a risk factor to lung g...
Current guidelines recommend severity of chronic obstructive pulmonary disease be graded by using forced expiratory volume in 1 s (FEV1). But this measurement is biased by thoracic gas compression depending on lung volume and airflow resistance. The aim of this study was to test the hypothesis that the effect of thoracic gas compression on FEV1 is greater in emphysema than chronic bronchitis be...
BACKGROUND Reduced forced expiratory volume in 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (FVC) are strong predictors of mortality and lung function is higher among individuals with exceptional longevity. However, genetic factors associated with lung function in individuals with exceptional longevity have not been identified. METHOD We conducted a genome wide association s...
BACKGROUND FEV1 is universally used as a measure of severity in COPD. Current thresholds are based on expert opinion and not on evidence. OBJECTIVES We aimed to identify the best FEV1 (% predicted) and dyspnea (mMRC) thresholds to predict 5-yr survival in COPD patients. DESIGN AND METHODS We conducted a patient-based pooled analysis of eleven COPD Spanish cohorts (COCOMICS). Survival analys...
Background: The etiology of dementia may partly be underpinned by impaired lung function via systemic inflammation and hypoxia. Objective: To prospectively examine the association between chronic obstructive pulmonary disease (COPD) subclinical impairments in risk dementia. Methods: In Rotterdam Study, we assessed incident participants with Preserved Ratio Impaired Spirometry (PRISm; FEV1/FVC?0...
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