OBJECTIVE To evaluate the outcome of genetic amniocentesis in twin gestations at Songklanagarind Hospital. MATERIAL AND METHOD This was a descriptive study that included all women with twin pregnancies who had a second trimester amniocentesis for chromosome study at the Maternal Fetal Medicine Unit, Department of Obstetrics and Gynecology, Songklanagarind Hospital from January 1998 through Ju...

Fetal loss in patients with antiphospholipid (aPL) antibodies has been ascribed to thrombosis of placental vessels. However, we have shown that inflammation, specifically activation of complement with generation of the anaphylotoxin C5a, is an essential trigger of fetal injury. In this study, we analyzed the role of the procoagulant molecule tissue factor (TF) in a mouse model of aPL antibody–i...

BACKGROUND Several factors may cause infertility and fetal loss. Blood groups antigens seem to be implied in the mechanisms of infertility and fetal loss. Maternal natural antibody can react against father's blood group antigens on spermatozoa. The effects of parental blood group system on infertility and fetal surveillance perceived by its manifestation in prezygotic (caused infertility) and p...

The observational study was carried out in a population of Polish breeding goats in 2007 to determine the prevalence of fetal loss and identify risk factors contributing to its occurrence. The multivariate model allowing to predict the risk of the occurrence of fetal loss in a herd in a study population was developed. Data on the occurrence of fetal loss, as well as of 28 hypothesized risk fact...

Infection and inflammation can disturb immune tolerance at the maternal-fetal interface, resulting in adverse pregnancy outcomes. However, the underlying mechanisms for detrimental immune responses remain ill defined. In this study, we provide evidence for immune programming of fetal loss in response to polyinosinic:polycytidylic acid (polyI:C), a viral mimic and an inducer of inflammatory mili...

Abstract Fetal loss occurs in 4 to 13% of dairy cattle worldwide with a subsequent $487 $1900 economic per pregnancy. Previous studies have identified SNPs associated fetal loss, but few investigated haplotypes (DNA that segregates offspring together) loss. The objective this study was identify Holstein heifers and cows conceived the first insemination. This consisted 529 (470 maintained pregna...

STUDY QUESTION Is there an association between discordance in embryonic growth and fetal loss at the time of the 11-14-week scan in twin pregnancies? SUMMARY ANSWER Regardless of the chorionicity, crown rump length (CRL) discordance at 7(+0)-9(+6) weeks is predictive of subsequent single fetal demise in the first trimester. WHAT IS KNOWN ALREADY Previous small studies have reported a variab...

background: in most cancer cases, the treatment choice for a pregnant patient is radiotherapy. in these patients, the abdomen is usually not exposed therefore fetus exposure is due to peripheral dose (pd). the purpose of this study was to estimate the fetal dose (the maximum pd in each pregnancy stage) for modalities available and to fabricate and evaluate a generally applicable fetal shield. m...