Exposure of adult specific-pathogen-free cats to methylnitrosourea resulted in increased susceptibility to infec tion by feline leukemia virus. A greater proportion of cats exposed to methylnitrosourea and feline leukemia virus (69%) became persistently viremic than those exposed to feline leukemia virus alone (17%). Segmented neutrophils were reduced by 90 to 99% within 3 days following expo s...

We cloned a cDNA fragment encoding a feline homologue of L-selectin (CD62L). The extracellular region of the feline CD62L fragment contained a calcium-dependent (C-type) lectin domain, an epidermal growth factor-like domain, and two Sushi/CCP/SCR domains. The flow cytometric analysis confirmed that the feline CD62L molecule, which was expressed 293T cells, retained an epitope recognized by an a...

Feline otitis is reviewed by evaluating the predisposing, primary, and secondary causes. Diagnostic and treatment options are summarized. Emphasis is placed on comparing feline and canine otitis.

Canine parvovirus (CPV) enters and infects cells by a dynamin-dependent, clathrin-mediated endocytic pathway, and viral capsids colocalize with transferrin in perinuclear vesicles of cells shortly after entry (J. S. L. Parker and C. R. Parrish, J. Virol. 74:1919-1930, 2000). Here we report that CPV and feline panleukopenia virus (FPV), a closely related parvovirus, bind to the human and feline ...

OBJECTIVES Feline leukemia virus (FeLV) is a potentially life-threatening oncogenic retrovirus. The p27 viral core protein is produced by the virus in infected feline cells, is found in the cytoplasm in several blood cells and can be free in the serum and plasma. ELISA or particle-based immunoassay are commonly used to detect the presence of the p27 core protein in samples obtained from blood. ...

Canine parvovirus (CPV) emerged as an apparently new virus during the mid-1970s. The origin of CPV is unknown, but a variation from feline panleukopenia virus (FPV) or another closely related parvovirus is suspected. Here we examine the in vitro and in vivo canine and feline host ranges of CPV and FPV. Examination of three canine and six feline cell lines and mitogen-stimulated canine and felin...

Feline herpesvirus-1 (FHV-1) atau feline viral rhinotracheitis (FVR) merupakan agen penyakit saluran respirasi atas yang penting pada kucing. Hal ini disebabkan transmisi mudah. Kucing terinfeksi melalui kontak langsung dengan sekreta konjungtival oronasal dari kucing terinfeksi. Tujuan studi yaitu melihat kondisi patologi secara makroskopik dan mikroskopis diduga virus rhinotracheitis. Organ d...

Although only recently discovered, feline adrenal disorders are becoming increasingly more recognized. Feline adrenal disorders include diseases such as hyperadrenocorticism (Cushing's syndrome) and hyperaldosteronism (Conn's syndrome). The clinical signs of feline hyperadrenocorticism, which include unregulated diabetes mellitus and severe skin atrophy, are unique to the cat. Other signs of fe...

background: the sole published data on feline heartworm infection in the philippines was reported four decades ago. the study therefore endeavoured to assess and provide an update on the current status of heartworm infection in domesticated feline species using serologic and parasitological ex-amination methods. methods: a total of 46 males and 54 females cats showing clinical signs of dirofila...

Feline calicivirus (FCV) is a highly contagious pathogen of cats that can be grown in cultured cells. FCV is used as a model to study nonculturable caliciviruses, such as noroviruses. We determined the complete genome sequence of the FCV 2280 strain from the American Tissue Culture Collection.