The structural analysis of sulfated carbohydrates such as glycosaminoglycans (GAGs) has been a long- standing challenge for the field of mass spectrometry. The dissociation of sulfated carbohydrates by collisionally- activated dissociation (CAD) or infrared multiphoton dissociation (IRMPD), which activate ions via vibrational excitation, typically result in few cleavages and abundant SO(3) loss...

We tested the hypotheses that 4 wk of exercise training would diminish the magnitude of vasoconstriction in response to sympathetic nerve stimulation and augment endothelium-dependent vasodilation (EDD) in resting skeletal muscle in a training intensity-dependent manner. Sprague-Dawley rats were randomly assigned to sedentary time-control (S), mild- (M; 20 m/min, 5% grade), or heavy-intensity (...

Next generation cellular wireless communication networks aim to provide a variety of quality-ofservice (QoS) sensitive packet based services to downlink users. Included amongst these are real-time multimedia services, which have stringent delay requirements. Downlink packet scheduling at the base station plays a key role in efficiently allocating system resources to meet the desired level of Qo...

BACKGROUND Endothelial dysfunction is a key vascular alteration in chronic kidney disease (CKD). Omega 3 (n-3) polyunsaturated fatty acids (PUFA) reduce vascular oxidative stress and inflammation. We investigated whether n-3 PUFA could reverse endothelial dysfunction in CKD by improving endothelial nitric oxide synthase (eNOS) function and oxidative stress. METHODS 5/6 nephrectomized male Wis...

We evaluated the inducibility of nitrate-dependent Fe(II)-EDTA oxidation (NDFO) in non-growth, chloramphenicol-amended, resting-cell suspensions of Dechloromonas sp. strain UWNR4 and Acidovorax sp. strain 2AN. Cells previously incubated with Fe(II)-EDTA oxidized ca. 6-fold more Fe(II)-EDTA than cells previously incubated with Fe(III)-EDTA. This is the first report of induction of NDFO by Fe(II).

We present the results on broadband X-ray properties of persistent black hole binaries GRS 1758$-$258 and 1E 1740.7$-$2942 using AstroSat, NuSTAR Swift-XRT observations carried out during 2016$-$2022. perform spectral modeling both sources after eliminating contamination in their \textit{LAXPC} spectra from nearby sources. Preliminary modelling Comptonization line emission ($\sim$ 6.4 keV) mode...

The temporal changes in left ventricular performance and hypertrophy after valve replacement for mitral regurgitation (MR) or stenosis (MS) are unclear. We studied 16 patients with MR and 17 patients with MS using echocardiography before and serially after surgery for an average of 15 months. Before surgery, average end-diastolic and end-systolic dimensions (EDD and ESD, respectively) and left ...

We tested the hypothesis that high fat (HF) feeding results in endothelial dysfunction in resistance arteries of epididymal white adipose tissue (eWAT) and is mediated by adipose tissue inflammation. When compared with normal chow (NC)-fed mice (n = 17), HF-fed male B6D2F1 mice were glucose intolerant and insulin resistant as assessed by glucose tolerance test (area under the curve; HF, 18,174 ...