OBJECTIVE To estimate how much more cardiovascular disease (CVD) mortality could be reduced in the United Kingdom through more progressive nutritional targets. METHODS Potential reductions in CVD mortality in the United Kingdom between 2006 (baseline) and 2015 were estimated by synthesizing data on population, diet and mortality among adults aged 25 to 84 years. The effect of specific dietary...

The effects of hydrogenated fats and butylated hydroxytoluene (BHT) in the diets of rats on the hepatic activation of benzo(a)pyrene, 2-acetylaminofluorene (AAF), and 2-aminofluorene by liver homogenates (S-9 fraction) were evaluated. The Salmonella/microsomal mutagenicity assay (Strain TA 98) was utilized to determine the mutagenic potential of the activated compounds. The S-9 fraction was obt...

A 2-day forum was convened to discuss the current status and future implications of reducing trans fatty acids without increasing saturated fats in the food supply while maintaining functionality and consumer acceptance of packaged, processed, and prepared foods. Attendees represented the agriculture and oilseed industry and oil processing, food manufacturing, food service, government, food tec...

¯abstract backgrounds: lipoprotein (a) or lp(a) is a cholesterol-rich particle with atherothrombogenic properties. plasma level of lp(a) varies in different populations, however, little data on normal range of lp(a) lipoprotein among iranian population is available objective: the aim of this study was to estimate the normal range of lp(a) and also its relationship with other lipoproteins in a g...

In 1883 a Department of Agricultural Chemistry was founded at the University of Wisconsin in the city of Madison. One hundred years later seems a fitting time to look back, to gain some perspective on the fortunes of that academic undertaking. It is in looking back that I discern an intriguing wave in the tide of time. Although in the first 30 years there was much of interest, I shall leave tha...

Fats and oils are water-insoluble compounds consisting of mainly triacylglycerols: three fatty acids esterified to a glycerol molecule. Products are generally called “fats” when they are solid at room temperature and “oils” when they are liquid at room temperature, although the terms are often used interchangeably. Edible fats and oils contribute to the flavor, texture, aroma, and mouthfeel of ...

The consumption of dietary fats have been long associated to chronic diseases such as obesity, diabetes, cancer, arthritis, asthma, and cardiovascular disease; although some controversy still exists in the role of dietary fats in human health, certain fats have demonstrated their positive effect in the modulation of abnormal fatty acid and eicosanoid metabolism, both of them associated to chron...

BACKGROUND Pharmacologic activation of the peroxisome proliferator-activated receptor gamma (PPAR-gamma) improves ovulatory function in women with polycystic ovary syndrome, and specific dietary fatty acids can affect PPAR-gamma activity. OBJECTIVE The objective of the study was to assess whether the intakes of total fat, cholesterol, and major types of fatty acids affect the risk of ovulator...

The aims of this study were to determine whether combining features of a western lifestyle in mice with trans fats in a high-fat diet, high-fructose corn syrup in the water, and interventions designed to promote sedentary behavior would cause the hepatic histopathological and metabolic abnormalities that characterize nonalcoholic steatohepatitis (NASH). Male C57BL/6 mice fed ad libitum high-fat...

THE milk-fats from goats and sheep are used, although only to a small extent, as substitutes for those of cows and buffaloes in India. The component fatty acids and glycerides of these two fats have been studied by methods recently developed [Hilditch et al., 1929; 1930; 1931] in the case of cow butter-fats, in order to compare their composition with those of the latter and, in certain respects...