نتایج جستجو برای: farahzads cda model

تعداد نتایج: 2106251  

Journal: :Blood 1983
D A Carson D B Wasson R Taetle A Yu

2-Chlorodeoxyadenosine (CdA), an adenosine-deaminase-resistant purine deoxynucleoside, is markedly toxic toward human T-lymphoblastoid cell lines in vitro and is an effective agent against L1210 leukemia in vivo. The present studies have examined the toxicity, and in some cases, metabolism, of CdA in (1) multiple established human cell lines of varying phenotype, (2) leukemia and lymphoma cells...

2014
John D. D'Amore Joshua C. Mandel David A. Kreda Ashley Swain George A. Koromia Sumesh Sundareswaran Liora Alschuler Robert H. Dolin Kenneth D. Mandl Isaac S. Kohane Rachel Badovinac Ramoni

BACKGROUND AND OBJECTIVE Upgrades to electronic health record (EHR) systems scheduled to be introduced in the USA in 2014 will advance document interoperability between care providers. Specifically, the second stage of the federal incentive program for EHR adoption, known as Meaningful Use, requires use of the Consolidated Clinical Document Architecture (C-CDA) for document exchange. In an effo...

2017
Mayura Halbe Brad Pietrzak David Fain Aswin Ramesh Greg Shaver James E. McCarthy Mike Ruth Edward Koeberlein

Cylinder deactivation (CDA) is a technology that can improve the fuel economy and exhaust thermal management of compression ignition engines (diesel and natural gas), especially at low loads and engine idling conditions. The reduction in engine displacement during CDA improves fuel efficiency at low loads primarily through a reduction in pumping work. During deactivation of a given cylinder, th...

Journal: :European Journal for Biomedical Informatics 2015

Journal: :British journal of haematology 2000
T Robak J Z Bloński M Kasznicki L Konopka B Ceglarek A Dmoszyńska M Soroka-Wojtaszko A B Skotnicki W Nowak J Dwilewicz-Trojaczek A Tomaszewska A Hellmann K Lewandowski K Kuliczkowski S Potoczek B Zdziarska J Hansz R Kroll M Komarnicki J Holowiecki P Grieb

Between January 1992 and January 1999, we treated 378 B-chronic lymphocytic leukaemia (CLL) patients with cladribine (2-CdA), and 255 of the patients were also treated with prednisone. A total of 194 patients were previously untreated, and 184 had relapsed or refractory disease after previous other therapy. Complete response (CR) was obtained in 111 (29.4%) and partial response (PR) in 138 (36....

Journal: :Acta haematologica 2011
Achiya Amir Orly Dgany Tanya Krasnov Peretz Resnitzky Ronit Mor-Cohen Michael Bennett Alain Berrebi Hannah Tamary

OBJECTIVE Congenital dyserythropoietic anemia (CDA) is characterized by ineffective erythropoiesis, binuclearity of erythroid precursors and secondary hemochromatosis. Recently, the gene mutated in CDA type II (CDA II), SEC23B, was identified. All Israeli patients with CDA II are of North African (mainly Moroccan) Jewish descent. We investigated the molecular basis of CDA II in those patients. ...

2007
Sanna Lehtonen

In this paper, I want to consider the possibility of applying feminist critical discourse analysis (CDA) to examine gender in children’s fantasy fiction. There are two major aspects in claiming that a critical linguistic, feminist approach to children’s fantasy might be needed. Firstly, considering the earlier applications of feminist CDA and CDA, one should note that these approaches have rare...

Journal: :Blood 2002
Joya Chandra Emma Mansson Vladimir Gogvadze Scott H Kaufmann Freidoun Albertioni Sten Orrenius

The purine nucleoside 2-chlorodeoxyadenosine (CdA) is often used in leukemia therapy. Its efficacy, however, is compromised by the emergence of resistant cells. In the present study, 3 CdA-resistant cell lines were generated and characterized. Their ability to accumulate 2-chloroadenosine triphosphate (CdATP) varied, reflecting differences in activities of deoxycytidine kinase (dCK) and deoxygu...

2013
X. Luciani S. Mounier R. Redon A. Bois

In this paper we introduce a new inner filters correction method for standard fluorometer. The Controlled Dilution Approach (CDA) deals with highly absorbing solutions using the Fluorescent Excitation-Emission Matrix of a controlled weak dilution. Along with the non linear FEEM of the original solution, these two informations allow to estimate the linearized FEEM. The method relies on inner fil...

1998
Ladjel Bellatreche Kamalakar Karlapalem Gopal K. Basak

Horizontal partitioning is a technique for reducing the number of disk accesses to execute a query by minimizing the number of irrelevant instances accessed. In this paper, we develop a cost model for query execution in the case of unpartitioned and horizontally partitioned classes. We present three algorithms to perform horizontal partitioning in OODBSs, namely: Cost-Driven Algorithm(CDA), Pre...

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