نتایج جستجو برای: fansidar
تعداد نتایج: 84 فیلتر نتایج به سال:
Toxoplasmic encephalitis (TE) is caused by Toxoplasma gondii infection and can be a life-threatening disease in immunocompromised patients. This study evaluated the rate of relapse associated with pyrimethamine-based maintenance therapy (i.e. secondary prophylaxis) in patients with human immunodeficiency virus (HIV) or AIDs treated prior to and after the common use (i.e. 1996) of highly active ...
BACKGROUND Home Based Management of fever (HBM) was introduced as a national policy in Uganda to increase access to prompt presumptive treatment of malaria. Pre-packed Chloroquine/Fansidar combination is distributed free of charge to febrile children <5 years. Persisting fever or danger signs are referred to the health centre. We assessed overall referral rate, causes of referral, referral comp...
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BACKGROUND Household surveys undertaken in Niger since 1998 have revealed steady declines in under-5 mortality which have placed the country 'on track' to reach the fourth Millennium Development goal (MDG). This paper explores Niger's mortality and health coverage data for children under-5 years of age up to 2012 to describe trends in high impact interventions and the resulting impact on childh...
BACKGROUND Malaria is a serious illness among children aged 5 years and below in Zambia, which carries with it many adverse effects including anemia and high parasites exposure that lead to infant and childhood mortality. Due to poor accessibility to modern health facilities, malaria is normally managed at home using indigenous and cosmopolitan medicines. In view of problems and implications as...
Introduction: Malaria is a public health problem for approximately 2.4 billion people, 40% of the world’s population, particularly in the tropical and subtropical countries. Countries in Asia, and Latin America, the islands of the South, West, and central pacific ocean are all affected. Drug resistance is the greatest challenge in combating against malaria. Drug resistance in malaria is now w...
Sir, British travellers to west Africa are at considerable risk of contracting malaria, principally Plasmodium falciparum malaria, in both rural and urban areas. Recent reports'-7 have indicated that resistance to chloroquine is now present in various countries in west Africa and it can be expected that chloroquine resistant 1 falciparum will increase in prevalence in these countries, and sprea...
Case Reports (Dr R F Miller) Case 1 A 25 year old Caucasian heterosexual man was found to be HIV I antibody positive in July 1989, when he presented to another hospital with cryptococcal meningitis. At this time his CD4+ count was 190 (normal range = 350-2,200)/mm3. Investigations showed normal urea and electrolyte levels and liver function tests; CT of the head was normal. Blood and urine cult...
One of the main problems in malaria control is the resistance of Plasmodium falciparum to chloroquine and some other antimalarial drugs. This resistance is now quite common in most regions where falciparum malaria is endemic. Between 1968 and 1976, two in-vivo studies were carried out in endemic areas in the south of Iran and they showed P. falciparum to be chloroquine-sensitive. In 1983, the D...
The study of evolutionary processes is necessarily retrospective, but past pathways can lull us into imagining that future changes will generally follow the same trajectory. The arms races between pathogens and drugs provide a particularly useful window to view these events in relatively short time frames. In PNAS, Pelleau et al. (1) provide an excellent demonstration of these selective changes...
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