background and aims: neurons are injured under physical, chemical and pathological conditions. the effect of peripheral nervous system injuries may return as retrograde to the cell body of neurons in central nervous system resulting in brain and spinal cord degeneration. because of high content of camphor and borneol, achillea biebersteinii from asteracea family may be effective in prevention t...

background: half of the cases of vision loss in people under 60 years of age have been attributed to age-related macular degeneration (amd). this is a multifactorial disease with late onset. it has been demonstrated that many different genetic loci are implicated in the risk of developing amd in different populations. in the current study, we investigated the association of high-temperature ‎re...

multiple sclerosis (ms) is a complex disease which is correlated with increasing inflammatory factors, demyelination and axonal loss. in this auto-immune disease, neuroinflammation is mediated by different types of t cells with macrophage/microglial activation and b cells involvement that interact in a collaborative manner. focal inflammation is the main cause for the onset of relapses and coul...

background nephrotoxicity is characterized and scored by many parameters such as vacuolization, dilatation, hyaline cast, debris or degeneration in injured renal tissue. in this short report, we attempt to find, the most correlated parameters with kidney tissue pathology damage score (pds) in cisplatin-induced nephrotoxicity. method a total of 207 normal and toxic rats’ kidney tissue (induced b...

age-related macular degeneration (amd) is the leading cause of blindness in old subjects. it is a multifactorial disease with both environmental and genetic factors playing some role in its pathogenesis. similar to many other genetic diseases, the inheritance pattern of amd does not fit into simple mendelian rules. these diseases are caused by the presence of multiple genetic factors and are ca...

Many animal and plant viruses rely on vectors for their transmission from host to host. Grapevine fanleaf virus (GFLV), a picorna-like virus from plants, is transmitted specifically by the ectoparasitic nematode Xiphinema index. The icosahedral capsid of GFLV, which consists of 60 identical coat protein subunits (CP), carries the determinants of this specificity. Here, we provide novel insight ...

Grapevine virus G (GVG) and grapevine H (GVH) (genus Vitivirus) are recently discovered viruses. Analysis of 38 samples from Sardinian cultivars for the presence GVG GVH was carried out using RT-PCR. All were also tested Pinot gris (GPGV) RT-PCR, leafroll -1, -2 -3, A (GVA) B (GVB), arabis mosaic (ArMV), fanleaf (GFLV) fleck (GFkV) multiplex confirmed in four vines, detected only one sample. In...