The study critically reviews the application, management and challenges of managed aquifer recharge (MAR) in Middle East North Africa (MENA) region through a survey 142 studies. reveals objectives methods MAR region. It also shows technical socioeconomic that significantly cause failure MENA countries. article concludes by presenting framework to evaluate feasibility it provides recommendations...

Developing drugs for cancer is a process as complex the disease itself. At planning stage of clinical trial an oncology drug, thorough and careful consideration must be given to choosing right study design endpoints/estimands, any bias introduced at outset would cascade down analysis eventually reporting results. The common designs drugs, their challenges, current perspectives (and dilemmas) in...

 The existence and non-existence of trend-resistant repeated measurement designs are investigated. Two families of efficient/optimal repeated measurement designs which are very popular among experimenters are shown to be trend-resistant or trend-resistant with respect to treatments.