Extramedullary plasmacytoma involving the heart is extremely rare. Primary extramedullary localizations are most commonly found in the head and neck region, with no radiologic evidence of additional skeletal lesions and normal bone marrow examination, but can occur in many other locations. They rarely occur in the heart and are commonly associated with multiple myeloma diagnosis. Here, we descr...

Intracranial plasmacytomas are an uncommon presentation of extramedullary relapse of multiple myeloma. The optimal management of extramedullary plasmacytomas remains unclear, with initial reports of bortezomib showing promising clinical results. We describe a case of multiple extracellular, including intracranial, plasmacytoma, with no evidence of marrow involvement, in a patient with relapsed ...

Plasmacytoma is a localized collection of malignant plasma cells. The disease is divided into Solitary plasmacytoma of the bone (SPB) and extramedullary plasmacytoma (EMP) which are both distinct entity. SPB usually occur in the bones characteristically affected in multiple myeloma and EMP was most frequently located in the oronasopharynx and paranasal sinuses, with a 15-30% incidence of region...

Solitary plasmacytoma (SP), histologically indistinguishable from multiple myeloma (MM), is a kind of malignant tumor characterized by the proliferation of monoclonal plasma cells. SP is an independent subtype of plasmacytoma, including extramedullary plasmacytoma and solitary plasmacytoma of bone (SPB) [1]. Most solitary plasmacytomas progress to MM, and are usually treated in the department o...

This report describes a case of gastric plasmacytoma which was diagnosed following an episode of haematemesis and melaena. The patient had a previous orbital plasmacytoma and subsequently developed aggressive disseminated disease with extensive skin and subcutaneous deposits but without marked marrow involvement until the terminal phase. Following the episode of haematemesis and melaena, endosc...

INTRODUCTION Plasmacytomas are malignant tumors characterized by abnormal monoclonal proliferation of plasma cells. They originate in either bone--solitary osseous plasmacytoma, or in soft tissue--extramedullary plasmacytoma (EMP). EMP represents less than 1% of all head and neck malignancies. CASE REPORT We presented a case of EMP of the nasal septum in a 44-year-old male who had progressive...

Plasmacytomas occurring in extramedullary sites are rare tumours, particularly so when located in the gastrointestinal tract. We report the case of a solitary extramedullary plasmacytoma arising in the duodenum and simulating a carcinoma of the head of the pancreas. Diagnostic and treatment options are discussed.

Plasmacytomas are localized tumors of monoclonal plasma cells without evidence of significant bone marrow infiltration or systemic myeloma, comprising B2–10% of all plasma cell neoplasms. Medullary plasmacytomas classically occur in the bone of the vertebrae or skull, whereas extramedullary plasmacytomas occur in the soft tissues, most frequently in the head and neck region involving the sinuse...

the diagnosis of gastric primary extramedullary plasmacytoma: a first case report Magnifying narrow-band imaging (NBI) endoscopy has been increasingly used in the diagnosis of early gastric cancer and is regarded as an effective diagnostic approach. This technique has been used to classify gastric cancer according to the tumor surface structure and microvessels [1,2]. We obtained a magnified NB...

To cite: Fernández-Bussy S, Labarca G, Folch E, et al. BMJ Case Reports Published online: [please include Day Month Year] doi:10.1136/ bcr-2012-007354 DESCRIPTION A 58-year-old man with a history of multiple myeloma was admitted to the hospital with progressive dyspnoea and hypoxemia. Chest examination revealed decreased breath sounds bilaterally. Blood examination revealed anaemia. Chest x-ray...