Natural biopolymers (carbohydrates and proteins) are the family of natural polymers that widely used in wound healing. This is due to their biocompatibility chemical structural similarity extracellular matrix (ECM). Wound healing a complex process requires multidisciplinary approach appropriate treatment product enable full recovery. Chronic nonhealing wounds significantly caused reduction. Cur...

Psoriasis is a chronic, recurrent, inflammatory and common skin disease of unknown aetiology. Amyloidosis defined as heterogeneous group diseases in which generally soluble plasma proteins accumulate the extracellular space insoluble abnormal fibrils. Type AA amyloidosis late severe complication chronic disorders some infections. Although psoriasis disease, development rare. Herein, we presente...

Transforming growth factor betas (TGF?s) are one of the most widespread and versatile cytokines. The three mammalian TGF? isoforms, ?1, ?2, and ?3, and their receptors regulate proliferation of neuronal precursors as well as survival and differentiation in neurons of developing and adult nervous system. Functions of TGF?s has a wide spectrum ranging from regulating cell proliferation and differ...

The aim of this study was to analyze the expression extracellular matrix (ECM) proteins in human endoneurium during aging. We harvested 15 cadaveric sural nerves, distributed 3 age groups (I: 25-44, II: 45-64, III: 65-86 years old). Histological sections were stained immunohistochemically for presence collagen type I, IV and laminin, ImageJ processing program used morphometrical analysis determ...

Vascular endothelial growth factors (VEGFs) are the family of extracellular signaling proteins involved in processes angiogenesis. VEGFA overexpression and altered regulation pathways lead to pathological angiogenesis, which contributes progression various diseases, such as age-related macular degeneration cancer. Monoclonal antibodies decoy receptors have been extensively used anti-angiogenic ...

The book Heat Shock Proteins (HSP) in Molecular and Cellular Biology of Human Diseases Volume 28 provides the most comprehensive up-to-date review on new exciting therapies that utilize mechanisms based heat shock response targeting various stress proteins as a promising therapeutic strategy for wide variety human diseases including all types cancers inflammatory diseases. Using an integrative ...

Salt and drought stress are important abiotic factors that negatively affect plant growth yield. To understand how these metabolism at the cellular level, we analyzed cation concentrations expression of extracellular proteins, as well their functions types. Cells industrially halophyte sugar beet were exposed to 300 mM NaCl 600 mannitol stressors in modified Gamborg B5 liquid medium (PG0). Seve...

www.sciencemag.org (this information is current as of June 14, 2007 ): The following resources related to this article are available online at http://www.sciencemag.org/cgi/content/full/316/5831/1600 version of this article at: including high-resolution figures, can be found in the online Updated information and services, http://www.sciencemag.org/cgi/content/full/316/5831/1600/DC1 can be found...