melissa officinalis l. is a medicinal plant with a large variety of pharmacological effects and traditional applications. this study aimed to evaluate the protective and antioxidant activities of the extract of m. officinalis aerial parts on human umbilical vein endothelial cells (huvecs) under oxidative stress induced by h 2 o 2 . cells were incubated with h 2 o 2 (0.5 mm, 2 h) after pretreatm...

Purification of extra-cellular cellulolytic enzymes from C e l l u l o mssp. strain 0, isolated from forest soil in the north of Iran , was studied by using gel filtration and ion-exchange chromatography. Two endo-glucanases (Endo-I & Endo-II) and one exo-glucanase (Exo-I) were purified to hornogenity . The purified enzymes had molecular weights of about 39.000,70.000 and 90.000 daltons for ...

BACKGROUND It is widely recognized that chronic obstructive pulmonary disease (COPD) includes a variety of extra pulmonary complications and comorbidities. Recently, adiponectin was shown to regulate cellular metabolism in humans. Cellular hydration state is affected by a variety of hormonal factors and regulates cellular metabolic state. Therefore, this study was designed to determine whether ...

Reactive oxygen species (ROS), by their very nature, are highly reactive, and it is no surprise that they can cause damage to organic molecules. In cells, ROS are produced as byproducts of many metabolic reactions, but plants are prepared for this ROS output. Even though extracellular ROS generation constitutes only a minor part of a cell's total ROS level, this fraction is of extraordinary imp...

The mechanism of cellular swelling induced by extra-cellular lactic acidosis and the effect of diuretics were studied using neuroblastoma-glioma hybrid (NG108-15) cells. The cells were incubated in one of three lactate concentrations (0, 15, or 30 mM), each of which was randomized to one of three pH groups (7.4, 6.2, or 5.0). Analysis of the swelling was measured using a Coulter counter techniq...

objective: echium amoenum fisch. & c.a. mey. is used for the treatment of various diseases in traditional medicine. this plant is a major source of anthocyanins with beneficial cardiovascular properties such as anti-atherosclerotic and antihypertensive effects. in the present study, the protective and antioxidant effects of anthocyanin-rich e. amoenum extract were evaluated on human vascular en...

Cyanobacterial blooms have been known since ancient times; however, they are currently increasing globally. Human and ecological health risks posed by harmful cyanobacterial recorded around the world. These mainly associated with their ability to affect ecosystem chain different mechanisms like production of cyanotoxins, especially microcystins. Their expansion effects led many researchers seek...

Irreversible hepatic fibrosis, an excessive production and accumulation of extra cellular matrix by stellate cells in the liver, becomes a remarkable economic burden global health care system.Low therapeutic efficacy undesirable systemic effect conventional therapies limit their clinical applications to targethepatic cells.

What is ECS and why is it important? rain tissue is essentially composed of two regions: cellular elements (neurons and glial cells), and the gap between the elements, which is known as the extra-cellular space (ECS; Figure 1) (Sykova & Nicholson, 2008). The ECS resembles the water phase of a foam and remains a highly connected domain even though it is convoluted in shape and may form dead-spac...