PURPOSE Radiotherapy has been the standard treatment of anal canal carcinoma for the last three decades. However, there are still many open questions such as optimal radiation technique, adequate boost dose or best chemotherapy regimen. Beside cure and local control, other important goals are sphincter salvage and avoidance of a permanent colostomy, i.e. morbidity minimization. MATERIAL AND M...

External beam radiotherapy (EBRT) is an effective treatment for symptomatic bone metastases from a variety of primary malignancies. Previous meta-analyses and systematic reviews have reported on the efficacy of EBRT on bone metastases from multiple primaries. This review is focused on the comparative effectiveness of single fraction radiotherapy versus multiple fraction radiotherapy for bone me...

There is limited detailed information regarding morbidity and toxicity following radiation treatment in gastric cancer. The curative effectivity of external radiotherapy necessitates exposure of normal tissues with significant radiation doses, and hence must be associated with an accepted rate of side effects. Based on the time of first treatment, complications can range from the acute side eff...

Introduction: Rectal and bladder cancer are the most common disease among young man. Although External Radiotherapy (EBRT) is one of the most effective treatment options introduced so far, the testis undesired radiation dose increases the risk of infertility and hormonal malfunctioning. The testicles are usually outside of the radiation field, but they can be exposed either to ...