External-beam radiation therapy with intracavitary high-dose-rate brachytherapy is the standard treatment modality for advanced cervical cancer; however, late gastrointestinal complications are a major concern after radiotherapy. While radiation proctitis is a well-known side effect and radiation oncologists make an effort to reduce it, the sigmoid colon is often neglected as an organ at risk. ...

Most patients referred for radiation therapy have large tumor volumes requiring high doses of radiation for control of locoregional disease. Dose escalation with external-beam radiation therapy is limited by tolerance of the surrounding normal structures. Brachytherapy is one method of delivering a higher radiation dose to the tumor while sparing the surrounding normal tissues, in an attempt to...

A prediction for the energy shift of the synchrotron spectrum of flat-spectrum radio quasars (FSRQs) during high-energy flares is presented. If the γ-ray emission of FSRQs is produced by Comptonization of external radiation, then the peak of the synchrotron spectrum is predicted to move to lower energies in the flare state. This is opposite to the well-known broadband spectral behavior of high-...