This review article gives a brief overview of some of the key legal challenges the OpenScienceLink, http://opensciencelink.eu (hereafter OSL) project faced with publishing biomedical research data online on an open access and re-use basis. Firstly, we give an overview of some of the key privacy challenges that the OSL project faced. Secondly, we analyse the intellectual property challenges that...

The object of this study was to develop hydroxypropyl methylcellulose (HPMC) based cephalexin extended release tablet, which can release the drug for six hours in predetermined rate. Twenty-one batches of cephalexin tablets were prepared by changing various physical and chemical parameters, in order to get required theoretical release profile. The influences of HPMC, microcrystalline cellulose ...

Peptide drugs are an exciting class of pharmaceuticals increasingly used for the treatment of a variety of diseases; however, their main drawback is a short half-life, which dictates multiple and frequent injections and an undesirable "peak-and-valley" pharmacokinetic profile, which can cause undesirable side-effects. Synthetic prolonged release formulations can provide extended release of biol...

Fast is a tool designed for the analysis of counter systems, i.e. automata extended with unbounded integer variables. Despite the reachability set is not recursive in general, Fast implements several innovative techniques such as acceleration and circuit selection to solve this problem in practice. In its latest version, the tool is built upon an open architecture: the Presburger library is man...

Metformin helps your body to better use the insulin your pancreas. . Many people find the Extended Release version is more tolerable. Pharmacokinetics and pharmacodynamics of extended-release glipizide GITS compared with immediate-release glipizide in patients with type II diabetes . 2 Answers (question resolved) Posted in: glipizide xl, glipizide, pharmacy, generic Answer: ER or XL means exten...

Nifedipine Extended-release Tablet depends for its action on the existence of an osmotic gradient between the contents of the tablet core and fluid in the gastrointestinal tract. Drug delivery is essentially constant as long as the osmotic gradient remains constant, and then gradually falls to zero. Upon swallowing, the biologically inert components of the tablet remain intact during gastrointe...

Correspondence: Stephen r Kraus University of Texas Health Science Center at San Antonio, Department of Urology, 7703 Floyd Curl Drive, MC, 7845, San Antonio, Texas 78229, USA Tel +1 (210) 567-5676 Fax +1 (210) 567-6868 email [email protected] Abstract: Overactive bladder (OAB) is a common condition which negatively impacts the quality of life of afflicted patients. This can result in alterati...

An extended release for surfactant ost think of exocytosis as an instantaneous process that once started cannot be fine-tuned. But on page 279, Haller et al. describe the exocytosis of surfactant from specialized lung cells (alveolar type II cells), and find that the degree and rate of pore expansion can be modified, thus controlling the rate of release of this vital agent from open pores. The ...

oxycodone is widely used to alleviate moderate-to severe acute pain, it is an effective analgesic for many types of pain, and is especially useful for paroxysmal spontaneous pain, steady pain, allodynia associated with postherpetic neuralgia, and it is also increasingly used in the management of cancer-related and chronic pain, oxycodone has been found to improve the quality of life of patients...