A genotoxic carcinogen, N-nitrosodimethylamine (NDMA), was detected as a synthesis impurity in some valsartan drugs 2018, and other N-nitrosamines, such N-nitrosodiethylamine (NDEA), were later sartan products. N-nitrosamines are pro-mutagens that can react with DNA following metabolism to produce adducts, O6-alkyl-guanine. The adducts result replication miscoding errors leading GC>AT mutations...

scans. We have not found any studies of MRI-induced injury to healthcare personnel from long-term exposure to EMFs or any studies correlating exposure levels to disease. Anesthesia personnel who provide limited or occasional care in the MRI environment run a risk of exposure to EMFs. Anesthesia providers should carefully consider their anesthetic technique to minimize the time spent in the MRI ...