نتایج جستجو برای: exotoxins
تعداد نتایج: 1304 فیلتر نتایج به سال:
Proinflammatory cytokines mediate the toxic effect of superantigenic staphylococcal exotoxins (SE). TJU103, a small nonpeptidic molecule that blocks the interaction between major histocompatibility complex class II and CD4 molecules inhibited SE-stimulated T-cell proliferation (by 92%) and production of tumor necrosis factor, interleukin 1beta, interleukin 6, and gamma interferon (by 66, 56, 76...
[This corrects the article DOI: 10.1371/journal.ppat.1005244.].
Pathogenic bacteria produce protein toxins to survive in the hostile environments defined by the host's defense systems and immune response. Recent progresses in high-throughput genome sequencing and structure determination techniques have contributed to a better understanding of mechanisms of action of the bacterial toxins at the cellular and molecular levels leading to pathogenicity. It is fa...
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