Oxidative stress has an important role in the pathogenesis of asthma. 8-Isoprostane is a prostaglandin (PG)-F2-like compound belonging to the F2 isoprostane class that is produced in vivo by the free radical-catalyzed peroxidation of arachidonic acid. 8-Isoprostane is a biomarker of oxidative stress, and its concentration is increased in the bronchoalveolar lavage fluid of patients with interst...

Background: Inhaled asbestos fibres can cause inflammation and fibrosis in the lungs called asbestosis. However, there are no non-invasive means to assess and follow the severity of the inflammation. Exhaled nitric oxide (NO) measured at multiple exhalation flow rates can be used to assess the alveolar NO concentration and bronchial NO flux, which reflect inflammation in the lung parenchyma and...

Introduction: Community-acquired pneumonia (CAP) and acute cardiogenic pulmonary oedema (ACPO) are common clinical conditions requiring hospital admission, but require different treatment. To assess whether exhaled breath analysis can distinguish between these, we measured exhaled breath condensate biomarkers and fractional exhaled nitric oxide (FENO) in 14 patients with CAP and 12 patients wit...

Small and medium extracellular vesicles, identified characterised in exhaled breath condensate induced sputum supernatants, might provide pathophysiological insights novel biomarkers severe asthma COPD patientshttps://bit.ly/3fiTnXY

We discuss the ordering of a spin-1 condensate when quenched from its paramagnetic phase to its ferromagnetic phase by reducing the magnetic field. We first elucidate the nature of the equilibrium quantum phase transition. Quenching rapidly through this transition reveals XY ordering either at a specific wave vector, or the "light-cone" correlations familiar from relativistic theories, dependin...

An odd number of gapless Dirac fermions is guaranteed to exist at a surface of a strong topological insulator. We show that in a thin-film geometry and under external bias, electron-hole pairs that reside in these surface states can condense to form a novel exotic quantum state which we propose to call "topological exciton condensate" (TEC). This TEC is similar in general terms to the exciton c...

We show that a many-atom Bose system at zero temperature has, in general, a liquid phase in addition to its well-known gaseous phase. A universal phase diagram is presented that is applicable to all Bose systems with a -C6/r6 type of interaction at large interparticle separations. We show that the predicted phase structure has implications on the stability of a gaseous Bose-Einstein condensate ...

In recent years, there has been increasing interest in noninvasive monitoring of airway inflammation and oxidative stress. Several volatile and nonvolatile substances can be measured in exhaled breath and have been suggested as potential biomarkers of these events. Exhaled gases, including carbon monoxide (CO), alkanes (ethane, pentane), and substances measured in breath condensate, such as hyd...