In 1960 Wilson and Mikity described a new form of respiratory disease in seven premature infants. In these infants the disease developed insidiously a few days or a few weeks after birth and was characterized by marked cyanosis, tachypnoea, exertional dyspnoea, wheezing, and coughing. All patients showed distinctive radiological changes. Clinical recovery always preceded resolution of the radio...

Three cases of exertional haemoglobinuria are described. So far, the cause of the underlying haemolysis in this condition has not been satisfactorily explained, but in the cases described, the haemoglobinuric episodes appeared to be related to traumatic damage to the soles of the feet. Experimental studies support the hypothesis that the intravascular haemolysis results from mechanical damage t...

NEW FINDINGS What is the central question of this study? Does the combination of a higher neural respiratory drive and greater dynamic mechanical ventilatory constraints during exercise in healthy women versus men form the mechanistic basis of sex differences in activity-related dyspnoea? What is the main finding and its importance? Sex differences in activity-related dyspnoea in health primari...

BACKGROUND Physiotherapy is an essential for the treatment of patients with chronic respiratory non-inflammatory diseases especially for chronic obstructive pulmonary disease (COPD). AIM To assess the effect of six months physiotherapy (PT) program on functional status in patients with COPD. MATERIAL AND METHODS The patients were divided into two groups according to the severity of the dise...

OBJECTIVE Hyperhidrosis can cause dehydration and exercise intolerance. There are several case reports of extremely high sweat rates in athletes. We present as case report of a 17-year-old male with the highest sweat rate recorded in the literature (5.8 L/h). Our goal was to determine if glycopyrrolate, an anticholinergic medication with primarily anti-muscarinic effects that is known to decrea...

A 22-year old woman visited the LAMB Hospital, Parbatipur, Dinajpur, Bangladesh, in February 2010, with exertional dyspnea for three weeks. She had had a normal vaginal delivery four months ago; 2-dimensional echocardiogram showed severe left ventricular dysfunction and biventricular thrombi, which resolved without complications after anticoagulation. Biventricular thrombosis with peripartum ca...

Mesenchymal soft tissue masses are uncommon tumours of the chest. Myofibroblastoma is a recently described entity consisting of cells with origin from the myoepethelial cell, mostly seen as benign well-circumscribed neoplasms of the breast tissue. Though usually classified as a benign lesion, rarely it can be multifocal and prone to recurrence. We describe below the case of a 26-year-old female...

The extracranial venous system is complex and variable between individuals. Until recently, these variations were acknowledged as developmental variants and were not considered pathological findings. However, in the last decade, the presence and severity of uni- or bi-lateral jugular venous reflux (JVR) was linked to several central nervous system (CNS) disorders such as transient global amnesi...

muscles as deliberate muscular relaxation relieves it. Masters and Johnson observed that "the muscles of the neck contract involuntarily in a spastic pattern" during intercourse .5 The second component, which may follow the first or arise without warning, occurs abruptly at the time of orgasm as a severe occipital or generalised ache, described as explosive or excruciating. The mechanism of thi...