نتایج جستجو برای: exercise induced bronchospasm

تعداد نتایج: 1134357  

   Cromolyn sodium, a mast cell stabilizing agent, provides an immediate protective effect against the exercise-induced bronchoconstriction while being used before the exercise. However, cromolyn is ineffective in reversing asthmatic bronchospasm; it is used as a maintenance therapy and has a prophylactic role in chronic asthma.    The purpose of this study was to determine the extent of change...

Journal: :Clinical reviews in allergy & immunology 2002
Miles Weinberger

Airways reactivity, hyper-reactivity, and hyper-responsiveness are terms used to describe airways for which there appears to be increased bronchial smooth muscle tone or responsiveness. Some patients with cystic fibrosis (CF) have concomitant asthma causing airway hyperresponsiveness as manifested by recurrent acute symptoms of dyspnea that is impressively responsive to an inhaled beta 2 agonis...

2006
P I MACFARLANE

Eighteen children aged 6 to 11 years old who fulfilled criteria for the diagnosis of neonatal meconium aspiration syndrome were investigated to find out the prevalence of previous and current respiratory symptoms, and abnormal pulmonary function tests, chest radiographs, and ventilation scans. Eleven of the 18 had no respiratory symptoms and eight of these had normal pulmonary function on testi...

Journal: :The European respiratory journal 2002
D G Peroni G L Piacentini A Pietrobelli A Loiacono W De Gasperi A Sabbion R Micciolo A L Boner

The aim of the study was to evaluate the protective effect of single-dose, combination treatment comprising montelukast (5 mg) and loratadine (10 mg), on exercise-induced bronchoconstriction in asthmatic children. The combination was compared to placebo, loratadine and montelukast alone. Nineteen children were enrolled in a double-blind randomised, single-dose, crossover study. For each treatme...

Journal: :The Journal of pharmacology and experimental therapeutics 2002
M Motasim Billah Nicola Cooper Michael Minnicozzi Julie Warneck Peng Wang John A Hey William Kreutner Charles A Rizzo Sidney R Smith Simon Young Richard W Chapman Hazel Dyke Nang-Yang Shih John J Piwinski Francis M Cuss John Montana Ashit K Ganguly Robert W Egan

N-(3,5-Dichloro-1-oxido-4-pyridinyl)-8-methoxy-2-(trifluoromethyl)-5-quinoline carboxamide (SCH 351591) has been identified as a potent (IC(50) = 58 nM) and highly selective type 4 phosphodiesterase (PDE4) inhibitor with oral bioactivity in several animal models of lung inflammation. N-(3,5-Dichloro-4-pyridinyl)-8-methoxy-2-(trifluoromethyl)-5-quinoline carboxamide (SCH 365351), the only signif...

Journal: :The European respiratory journal 2005
Z Csoma E Huszár E Vizi G Vass Z Szabó I Herjavecz M Kollai I Horváth

In asthmatic patients, airway obstruction provoked by exercise challenge is accompanied by an increase in plasma adenosine level. In this study, the current authors investigated if exercise-induced bronchoconstriction was associated with local changes of adenosine concentration in the airways. Oral exhaled breath condensate (EBC) collection (5-min duration) and forced expiratory volume in one s...

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