Introduction: Er3+:Yb3+ codoping has become an effective method for producing short, efficient lasers and amplifiers in the long haul telecommunications wavelength range. Ytterbium codoping increases the pump absorption near 980nm and efficient energy transfer between the Yb’’ and the Er3+ ions enables the operation of centimetre long lasers with low Er” concentrations. This mechanism was first...

Distributions over matrices with exchangeable rows and infinitely many columns are useful in constructing nonparametric latent variable models. However, the distribution implied by such models over the number of features exhibited by each data point may be poorly-suited for many modeling tasks. In this paper, we propose a class of exchangeable nonparametric priors obtained by restricting the do...

A hypergraph is a generalization of a graph in which an edge may contain more than two vertices. Hereditary hypergraphs are particularly important because they arise in mathematics as the class of monotone subsets, in statistics as the class of factorial models, in topology as simplicial complexes and in algebra as the free distributive lattice. An exchangeable random hypergraph consists of a p...

Little information is available on chemical forms of heavy metals on integrate plant roots. KNO3 (1 M), 0.05M EDTA at pH6 and 0.01 M HCl were used sequentially to extract the exchangeable, complexed and precipitated forms of Cu(II) and Cd(II) from soybean roots and then to investigate chemical form distribution of Cu(II) and Cd(II) on soybean roots. Cu(II) and Cd(II) adsorbed on soybean roots w...

Metallothionein, a two-domain protein, naturally binds seven gram atoms of divalent ions such as Zn and Cd. Four of the metals (M1, M5, M6 and M7) are found in the alpha-domain and three (M2, M3 and M4) in the beta-domain. Previous studies have shown that metals in the beta-domain are more readily exchangeable, and the level of avidity is site specific. By semi-empirical MNDO modified neglect o...

We present the synthesis and characterization of octaarginine-conjugated Copper-Gad-2 (Arg8CG2), a new copper-responsive magnetic resonance imaging (MRI) contrast agent that combines a Gd3+-DO3A scaffold with a thioether-rich receptor for copper recognition. The inclusion of a polyarginine appendage leads to a marked increase in cellular uptake compared to previously reported MRI-based copper s...

A general method for tritiating proteins, peptides, and other nonvolatile organic compounds has been developed. A carefully controlled particle beam composed of T3+ and T2+ ions and fast T2 molecules is accelerated into a sample target within a vacuum chamber. This beam method has been used to tritiate ribonuclease A, porcine pancreatic elastase, thermolysin, soybean trypsin inhibitor, alpha 1-...

The pathophysiological mechanisms of progressive demyelinating disorders including multiple sclerosis are incompletely understood. Increasing evidence indicates a role for trace metals in the progression of several neurodegenerative disorders. The study of Skogholt disease, a recently discovered demyelinating disease affecting both the central and peripheral nervous system, might shed some ligh...

Tailings produced during bitumen extraction from surface-mined oil sands ores (tar sands) comprise an aqueous suspension of clay particles that remain dispersed for decades in tailings ponds. Slow consolidation of the clays hinders water recovery for reuse and retards volume reduction, thereby increasing the environmental footprint of tailings ponds. We investigated mechanisms of tailings conso...