Objectives. Anemia is a major public health problem throughout the world which assumes prominence in pregnant mothers. Patients with severe anemia continue to present themselves at term or in labor. This study was conducted to compare the improvements in hematological parameters of patients receiving partial exchange blood transfusion and transfusion of packed cells without exchange. Methods. O...

I N PREVIOUS papers,1 ’ a method of treating erythroblastotic infants by cxchange transfusion was describcd. In the cases reported, the disease had been produced by sensitization to the Rh factor. Despite the publication of several well documented reports,6 it is still not universally appreciated that typical erythroblastosis can also, though rarely, result from sensitization to the A and B fac...

Partial exchange transfusion with a cell-free hemoglobin (Hb) polymer during transient middle cerebral artery occlusion (MCAO) reduces infarct volume but fails to increase blood flow, as might be expected with the induced decrease in hematocrit. In ischemic brain, endothelin antagonists are known to produce vasodilation. In nonischemic brain, pial arterioles constrict after Hb exchange transfus...

where v is the total exchanged volume, V is the patient's blood volume and e is the transcendental number, base of the natural logarithm. However, he later stated that his formula was not correct because it did not take into consideration the difference between the patient's haematocrit and that of the transfused blood. Moreover, according to others, even when the two haematocrits happen to be ...

The changes in plasma thyroid hormone concentration were studied during exchange transfusion performed for haemolytic disease. 24 transfusions were performed using blood preserved with acid-citrate and dextrose and in 11 cases 10 or 50 mug glucagon was added to the donor blood. Plasma tri-iodothyronine (T3), thyroxine (T4), thyrotropin (TSH), thyroid hormone binding capacity, and free thyroxine...

A patient with homozygous sickle cell disease showed a reduced incidence of painful crises as a result of regular exchange transfusion, but on three occasions when transfusion treatment was interrupted, a painful crisis occurred. Onset of painful crisis was associated with raised packed cell volume (PCV) or percentage of haemoglobin S (HbS%), or both. Measurement of whole blood viscosity using ...

Wood, Ben, Comley, Ann, and Sherwell,Janet (1970). Archives of Disease in Childhood, 45, 59. Effect of additional albumin administration during exchange transfusion on plasma albumin and reserve albumin-binding capacity. A total of 33 infants undergoing exchange transfusion for hyperbilirubinaemia was divided into two albumin-treated groups and a control group. Both albumin-treated groups showe...

Because of complicated rheological issues related with sickle cell blood, there exists a practical need to rationally determine critical hematocrit in transfusions for sickle cell patients. In this research, two major effects, i.e. oxygen concentration and hematocrit, are considered in a theoretical hydrodynamic model incorporating oxygen transport and lubrication theory. The pressure drop depe...

The overall incidence of glucose-6-phosphate dehydrogenase (G6PD) deficiency in Iranian population is estimated around 10%-14.9%. G6PD deficiency is an X-linked disorder and 80% of donors are usually male. At present, donors’ blood is not routinely screened for G6PD deficiency in Iran blood bank where for detecting such enzyme deficiency, reliance is placed on pre-donation data. Thus, the G6PD ...

Plasma concentrations of calcium, phosphate, citrate, albumin, and parathyroid hormone (PTH) were measured during and after exchange transfusion of infants suffering from haemolytic disease using blood anticoagulated with acid-citrate and dextrose (ACD) or heparin. Pretransfusion plasma PTH and phosphate both correlated positively with postnatal age but not with each other. Transfusion with ACD...