The present study evaluated the hypothesis that the effects of hypoxia on sheep pregnancies at high altitude (HA) are mediated by oxidative stress and that antioxidant vitamins may prevent these effects. Both HA native and newcomer ewes were maintained at an altitude of 3,589 m during mating and pregnancy. Control low altitude (LA) native ewes were maintained at sea level. Half of each group re...

The thyroid structural changes in pregnant ewes and their fetuses were investigated. Out of 100 pairs of thyroid glands collected from ewes and their fetuses at the local municipal abattoir in Ahvaz city of Khuzestan province, multiple lesions were seen in 59% and 21% of the thyroid glands of ewes and fetuses, respectively. Histologically, ninety nine lesions in the ewes and twenty two lesions...

Two experiments were conducted to examine effects of d-á-tocopherol (vitamin E) on colostrum immunoglobulin G (IgG) titers and preweaning lamb performance. Trial 1 consisted of 86 Suffolk ewes receiving either no vitamin E (control) or 1500 IU vitamin E on d-28 prepartum. From the 86 ewes, a subset of 25 ewes was randomly chosen for an intensive analysis of ewe serum and colostrum IgG and lamb ...

The objective of this experiment was to compare vaccination schedules for ewes and their lambs to raise antibody concentrations to epsilon-toxin of Clostridium perfringens, the causative agent of enterotoxemia. Half of 200 Finnsheep x Dorset ewes were vaccinated with C. perfringens type D toxoid vaccine 3 wk before lambing. Serum samples were obtained from 20 ewes that were to be vaccinated and...

The ovaries of 3 groups of Merino ewes were examined for corpora lutea by laparoscopy every 17 days between 28.3.74 and 16.6.75. During the 1974 breeding season the mean body weight of the ewes was maintained at 37 kg. Between the 1974 and -1975 breeding seasons the nutrition of the ewes was varied to give groups of ewes with mean body weights of 37, 41 and 46 kg; groups of ewes of low, medium ...

Pregnancy is characterized by increased plasma adrenocorticotropic hormone (ACTH) and cortisol. Studies suggest that progesterone acts as an antagonist at mineralocorticoid receptors. Therefore, we tested the hypothesis that chronic progesterone, produced by treatment of nonpregnant ewes or during pregnancy, will result in increased plasma ACTH relative to the plasma cortisol concentrations. We...

The effect of level of dietary energy and protein intake on reproductive performance was studied in 110 Finn-cross ewe lambs and in 404 Finn-cross yearling ewes during late gestation. Nitrogen metabolism was studied in 26 ewe lambs and 23 yearling ewes. Increasing digestible energy and crude protein intake for ewe lambs and yearling ewes during late gestation increased (P<.05) ewe average daily...

Two commercially available progestogen products for cattle, melengestrol acetate (MGA) and norgestomet (SMB), were evaluated for their ability to induce synchronized estrus in anovulatory ewes. Seasonally anestrous ewes (n = 232) were randomly assigned to one of seven treatments: 1) control (C); 2) MGA only (OMGA; .3 mg of MGA/d); 3) MGA+zeranol (RMGA; 2.5 mg of zeranol); 4) MGA+PG-600 (PMGA; 4...

These studies test the hypothesis that pregnancy alters the feedback effects of cortisol on stimulated ACTH secretion. Ewes were sham-operated (Sham), or adrenalectomized (ADX) at approximately 108 days gestation and replaced with aldosterone (3 microg x kg(-1) x day(-1)) and with cortisol at either of two doses (ADX + 0.6 and ADX + 1 mg x kg(-1) x day(-1)); ewes were studied during pregnancy a...

These studies test the hypothesis that the increased adrenocorticotropic hormone (ACTH) and cortisol in pregnancy reflect a reset of regulated plasma cortisol concentrations. Ewes were sham operated (Sham) or adrenalectomized (ADX) at ∼108 days gestation. Adrenalectomized ewes were replaced with aldosterone (3 μg ⋅ kg-1 ⋅ day-1) and with cortisol at either of two doses (ADX + 0.6 and ADX + 1.0 ...