نتایج جستجو برای: event study
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در محیط محاسبات فراگیر، تمام وسیله هایی که قصد برقراری ارتباط با یکدیگر را دارند با رویدادها سر و کار دارند. به همین دلیل، کشف سرویس ها و مدیریت رویدادها در این محیط از حساسیت و پیچیدگی محسوسی برخوردار است. با توجه به اهمیت موضوع، هدف این رساله ارائه ی شیوه ایست که با استفاده از پایگاه داده ی فعال و به کارگیری قوانین eca (event, condition, action)، پیچیدگی رویدادهای بین وسیله ها را کاهش داده ...
INTRODUCTION Clinical course and treatment response may vary according to race/ethnicity in multiple sclerosis (MS) patients. Delayed-release dimethyl fumarate (DMF; also known as gastro-resistant DMF) demonstrated significant efficacy and a favorable benefit-risk profile in relapsing-remitting MS (RRMS) patients in the 2-year phase III DEFINE/CONFIRM studies. METHODS In this post hoc analysi...
INTRODUCTION mirabegron is a β3-adrenoceptor agonist developed for the treatment of symptoms of overactive bladder (OAB). As the prevalence of OAB increases with age, a prospective subanalysis of individual and pooled efficacy and tolerability data from three 12-week, randomised, Phase III trials, and of tolerability data from a 1-year safety trial were conducted in order to evaluate the effica...
We previously reported the results of a phase II/III, double-blind, randomized controlled study in Chinese women (NCT00779766) showing a 94.2% (95% confidence interval: 62.7-99.9) HPV-16/18 AS04-adjuvanted vaccine efficacy (VE) against cervical intraepithelial neoplasia grade 1 or higher (CIN1+) and/or 6-month (M) persistent infection (PI) with a mean follow-up of <2 years, and immunogenicity u...
Gepotidacin is a novel, first-in-class, triazaacenaphthylene antibacterial agent which has in vitro activity against causative pathogens of acute bacterial skin and skin structure infections (ABSSSIs). This phase 2, randomized, 2-part, multicenter, dose-ranging, response-adaptive study with optional intravenous-oral switch evaluated the efficacy and safety of gepotidacin for the treatment of Gr...
AIMS SB4 has been developed as a biosimilar of etanercept. The primary objective of the present study was to demonstrate the pharmacokinetic (PK) equivalence between SB4 and European Union -sourced etanercept (EU-ETN), SB4 and United States-sourced etanercept (US-ETN), and EU-ETN and US-ETN. The safety and immunogenicity were also compared between the treatments. METHODS This was a single-bli...
In recent years, disaster management has been the focus of attention since disasters have been associated with huge destructions and consequences. Basically, disaster management techniques aim at the prevention and mitigation works as well as promotion of resilience. Haddon’s matrix was proposed as a conceptual model to understand the event and provide preventive measures in the field of injur...
BACKGROUND Obesity is a complex problem that is now considered a chronic metabolic disease. In Korea, phentermine has been widely used for the treatment of obesity in the primary care setting since 2004. However, there have been very few studies on the safety and efficacy of phentermine. To investigate the safety and efficacy of this drug, a postmarketing surveillance study was performed. MET...
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