نتایج جستجو برای: etomidate
تعداد نتایج: 998 فیلتر نتایج به سال:
The specific mechanisms underlying general anesthesia are primarily unknown. The intravenous general anesthetic etomidate acts by potentiating GABA(A) receptors, with selectivity for beta2 and beta3 subunit-containing receptors determined by a single asparagine residue. We generated a genetically modified mouse containing an etomidate-insensitive beta2 subunit (beta2 N265S) to determine the rol...
We evaluated the effect of N(G)-nitro-L-arginine-methyl-ester (l-NAME, a nitric oxide synthase [NOS] inhibitor) and L-arginine (nitric oxide substrate) on cerebral mitochondrial dysfunction (hereafter referred to as "injury") after temporary middle cerebral artery occlusion (MCAo) during halothane or etomidate anesthesia in spontaneously hypertensive rats. Sixty minutes before MCAo, rats were r...
Editor—We read with interest the study by Nyman and colleagues 1 concerning etomidate and injection pain in children. It is well accepted that a single bolus dose of eto-midate can result in adrenal suppression in adult patients, not only the critically ill 2 but also in healthy young adults. 3 Single bolus dose etomidate has also been linked with impaired adrenal function in critically ill chi...
background: etomidate and propofol are common anesthetic agents. previous studies say that etomidate can be used in patients with limited hemodynamic reserve and propofol can lead to more hemodynamic instabilities. th is study was performed to explore the cardiovascular response during the induction of anesthesia with etomidate or for comparison, propofol in elective orthopedic surgeries. mater...
BACKGROUND This prospective and randomized study was designed to compare safety, potential complications, and patient and examiner satisfaction of 2 anesthetic combinations - etomidate-remifentanil and propofol-remifentanil - in elderly patients undergoing diagnostic gastroscopy. MATERIAL AND METHODS A group of 720 patients, aged 60-80 years, scheduled for diagnostic gastroscopy under sedatio...
To define the role of vecuronium in the occurrence of bradyarrhythmia, haemodynamic changes after the induction of anaesthesia were studied in 96 patients undergoing coronary artery bypass grafting. Patients were assigned to one of six groups according to different combinations of induction agents (etomidate 0.3 mg kg-1 or thiopentone 3 mg kg-1, with fentanyl 0.003 mg kg-1; etomidate 0.4-0.5 mg...
BACKGROUND AND OBJECTIVES Reducing pain on injection of anesthetic drugs is of importance to every anesthesiologist. In this study we pursued to define if pretreatment by granisetron reduces the pain on injection of etomidate similar to lidocaine. METHODS Thirty patients aged between 18 and 50 years of American Society of Anesthesiologists physical status class I or II, whom were candidates f...
Introduction: Electroconvulsive therapy (ECT) is a widely used and safe evidence based intervention in modern psychiatry as a treatment for a variety of psychiatric disorders. The choice of anesthetic agent may influence recovery pattern, hemodynamic effects, seizure activity, cognitive functions and cost-effectiveness of the procedure. There is relative paucity of literature in this regard. Gi...
BACKGROUND Etomidate is a sedative hypnotic that is often used in critically ill patients because it provides superior hemodynamic stability. However, it also binds with high affinity to 11beta-hydroxylase, potently suppressing the synthesis of steroids by the adrenal gland that are necessary for survival. The authors report the results of studies to define the pharmacology of (R)-ethyl 1-(1-ph...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید