The polyspecific organic cation transporters 1 and 2 (Oct1 and -2) transport a broad range of substrates, including drugs, toxins, and endogenous compounds. Their strategic localization in the basolateral membrane of epithelial cells in the liver, intestine (Oct1), and kidney (Oct1 and Oct2) suggests that they play an essential role in removing noxious compounds from the body. We previously sho...

Introduction The paramagnetic properties of divalent manganese cations (Mn) and their in vivo resemblance to calcium cations (Ca) has led to their use in morphological [1] and neural pathway [2] imaging. Mn is taken up through Ca-channels during neural activity and subsequently transported anterograde along microtubules at a velocity equivalent to fast axonal transport thereby making the metal ...

The understanding of hydrogen attachment to carbonaceous surfaces is essential to a wide variety of research fields and technologies such as hydrogen storage for transportation, precise localization of hydrogen in electronic devices and the formation of cosmic H2. For coronene cations as prototypical Polycyclic Aromatic Hydrocarbon (PAH) molecules, the existence of magic numbers upon hydrogenat...

BACKGROUND There are more than 350 wastewater treatment plants distributed across different parts of Oman. Some of them produce large quantities of domestic sewage sludge, particularly this study focused on characterizing domestic sludge of six treatment plants that may contain various pollutants, therefore the proper management of domestic sewage sludge is essential. METHODS Samples of domes...

Mutations at the natural resistance-associated macrophage protein 1 (Nramp1) locus cause susceptibility to infection with antigenically unrelated intracellular pathogens. Nramp1 codes for an integral membrane protein expressed in the lysosomal compartment of macrophages, and is recruited to the membrane of phagosomes soon after the completion of phagocytosis. To define whether Nramp1 functions ...

in this paper, polyacrylamide/chromium acetate gel polymer system was prepared as water shut-off system to control water production in one of the iranian oil reservoirs condition. effect of various parameters such as temperature (90 °c) and water formation from view point of salinity and divalent cations, was evaluated on the gelation kinetic and gel strength using bottle testing method. the re...

a proton nmr method for the drtermination of salvation numbers of alkaline earth cations with hexamethyl phosphoramide (hmpa) in nitromethane (nm) as diluents is described. the method is based on monitoring the resonance frequency of hmpa protons as a function of hmpa / metal ion molar ratio at constant metalion concentration. the average salvation number of cations,  , at any hmpa / metal ion ...