BACKGROUND Achalasia cardia is an uncommon disease in children particularly in infants. We present 8 cases of achalasia who were encountered over a 12-year period. In infantile achalasia, respiratory symptoms predominate and vomiting may easily be mistaken for gastroesophageal reflux (GER). Vomiting of uncurdled milk is characteristic of achalasia. METHODS In this retrospective study, the dat...

A 63-year-old male, chronic alcohol consumer, presented with progressively increasing dysphagia of 6 months duration. Upper gastrointestinal endoscopy revealed dilated esophagus with residue along with esophageal varices. Esophageal manometry revealed findings suggestive of classic achalasia cardia. Endoscopic ultrasound (EUS) examination revealed peri-esophageal collaterals as well as prominen...

The pathogenesis of achalasia involves the degeneration of enteric and autonomic nervous systems with resultant effects on esophageal motility. The neural degeneration could affect visceral sensation in achalasia. The aim of this study was to examine mechanosensitivity and chemosensitivity in patients with achalasia. Perceptual responses to esophageal distension and acid perfusion were assessed...

Secondary achalasia or pseudoachalasia is a rare esophageal motor abnormality, which mimics primary achalasia; it is not easily distinguishable from idiopathic achalasia by manometry, radiological examination, or endoscopy. Although the majority of reported pseudoachalasia cases are associated with neoplasms at or near the esophagogastric (EG) junction, other neoplastic processes or even chroni...

Achalasia is a primary disorder of esophageal motility. It classically presents with dysphagia to both solids and liquids but may be accompanied by regurgitation and chest pain. The gold standard for the diagnosis of achalasia is esophageal motility testing with manometry, which often reveals aperistalsis of the esophageal body and incomplete lower esophageal sphincter relaxation. The diagnosis...

BACKGROUND The named primary esophageal motility disorders (PEMDs) are achalasia, diffuse esophageal spasm (DES), nutcracker esophagus (NE), and hypertensive lower esophageal sphincter (HTN-LES). Although the diagnosis and treatment of achalasia are well defined, such is not the case with the other disorders. HYPOTHESIS (1) Symptoms do not reliably distinguish PEMDs from gastroesophageal refl...

Muscularis propria of the esophagus is organized into circular and longitudinal muscle layers. Goal of this review is to summarize the role of longitudinal muscle in physiology and pathophysiology of esophageal sensory and motor function. Simultaneous manometry and ultrasound imaging that measure circular and longitudinal muscle contraction respectively reveal that during peristalsis 2 layers o...

Achalasia cardia, a primary esophageal motility disorder of unknown etiology involving lower twothird of esophagus and lower esophageal sphincter (LES), can be specifically diagnosed by gold standard method, manometry, which shows abnormal LES relaxation and absent or vigorous peristalsis. In our study, 125 patients were admitted with dysphagia, regurgitation of food, vomiting, chest pain, retr...

Achalasia is a primary esophageal motility disorder that involves failure of the lower sphincter to relax in response swallowing. Specifically, becomes hypertensive, and there an absence peristalsis esophagus. The pathophysiology thought be due loss inhibitory nerve function from autoimmune attack targets myenteric nerves. As result, these abnormalities lead functional obstruction at gastroesop...

between 1993-1996 seventy-three consecutive patients (33 m, 40 f, mean age 35.4) with newly diagnosed achalasia underwent one or more pneumatic dilatations with the rigiflex balloon using a protocol of graded dilatation with a fixed inflation pressure of 10 psi and constant duration of 30 seconds for all patients without using fluoroscopy. using vantrappen's classification for assessment o...