<em><span lang="EN-US">Bacteria are one of the pathogenic microorganisms that cause infection. Honey has been used in ancient times as a topical antibacterial for treatment surface infections, especially open wounds. Allicin is active substance garlic and properties. The purpose this study was to determine whether fermented pure honey single had an inhibitory effect on Esherichia co...

Background The beta lactam antibiotics are predominant therapeutic agents against a number of infectious diseases. The production of the enzyme beta lactamase by microbes which hydrolyses the beta lactam antibiotics is an important mechanism of resistance. This study aimed to determine prevalence, phenotypic patterns, and ESBLproduction status both phenotypic and genotypic for the CTX –M type E...

  Objective(s): The major antibiotic efflux pump of Esherichia coli is AcrAB-TolC. The first part of the pump, AcrAB, is encoded by acrAB operon. The expression of this operon can be kept elevated by overexpression of an activator, MarA following inactivation of MarR and AcrR repressors due to mutation in encoding genes, marR and acrR, respectively. The aims of this research were to us...

MarA activates two membrane dependent mechanisms of resistance to different antibiotics, such as ciprofloxacin and tetracycline, including promotion of outflux and inhibition of influx of antibiotics. Thus, MarA causes multiple antibiotic resistance phenotype. The activation of these mechanisms needs overexpression of marA. This could happen through mutation in marR. Thus, the aim of this study...

Background. To evaluate the risk factors of fluoroquinolone resistant or ESBL-producing E coli infections after prostate biopsy under flouroquinolone prophylaxis Methods. From January 2003 to December 2012, we evaluated the records of 2215 patients who underwent TRUS guided 12-core prostate biopsy under flouroquinolone prophylaxis. The risk factors including age, diabetes mellitus, hypertension...

objective(s): the major antibiotic efflux pump of esherichia coli is acrab-tolc. the first part of the pump, acrab, is encoded by acrab operon. the expression of this operon can be kept elevated by overexpression of an activator, mara following inactivation of marr and acrr repressors due to mutation in encoding genes, marr and acrr, respectively. the aims of this research were to use e. coli m...

OBJECTIVE(S) The major antibiotic efflux pump of Esherichia coli is AcrAB-TolC. The first part of the pump, AcrAB, is encoded by acrAB operon. The expression of this operon can be kept elevated by overexpression of an activator, MarA following inactivation of MarR and AcrR repressors due to mutation in encoding genes, marR and acrR, respectively. The aims of this research were to use E. coli mu...