MEDICINE & HEALTH/RHODE ISLAND Lyme borreliosis results from infection by the spirochete Borrelia burgdorferi. The ixodes scapularis tick, commonly known as the deer tick, acts as a vector and is endemic in coastal New England and the Mid-Atlantic States. The disease is divided into early (after 3-32 days incubation) and late stages, as well as limited and disseminated disease. Limited disease ...

A 22-year-old woman was admitted to the hospital with fevers, neck pain, the “worst headache of her life,” and bilateral knee pain. The patient reported a history of uveitis and recounted a recent tick exposure. Physical examination revealed multiple red, circular, nonpruritic skin lesions with bull’s-eye appearances that were approximately 2 inches in diameter and located on the patient’s legs...

Studies on frequencies of serum antibodies to outer surface proteins (Osps) in Lyme disease have produced conflicting results. Osp antigens (A, B, and C) enriched by butanol extraction, which aids band identification in immunoblotting, were used to test sera for IgG antibody to Osp antigens from Borrelia burgdorferi isolates from each subspecies (sensu stricto, afzelii, and garinii). Individual...

Erythematous rashes that are suggestive of early Lyme disease have been associated with the bite of Amblyomma americanum ticks, particularly in the southern United States. However, Borrelia burgdorferi, the causative agent of Lyme disease, has not been cultured from skin biopsy specimens from these patients, and diagnostic serum antibodies usually have not been found. Borrelia lonestari sp nov,...

Aeschlimann A. Ixodes ricinus, Linn6, 1758 (Ixodoidea; Ixodidae). Essai pr6liminaire de synthese sur la biologie de cette espece en Suisse. Acta Trop (Basel) 1972;29:321-40. 2 Golding D, Champion RH, Rook A, Roberts SOB. Erythema chronicum migrans in Britain. Br Med J 1978 ;ii :1087. 3 Steere AC, Malawista SE, Snydan DR, Andiman WA. A cluster of arthritis in children and adults in Lyme Connecti...

The causative agent of Lyme disease, Borrelia burgdorferi, is a highly neurotropic organism that not only can produce symptomatic neurologic disease but also can exist dormant within the central nervous system (CNS) for long periods. Two distinct types of neuroborreliosis occur at different stages of Lyme disease. Second-stage Lyme meningitis resembles aseptic meningitis and is often associated...

Six adult solid-organ transplant recipients who had chronic drug-induced immunosuppression and who presented with solitary erythema migrans were treated with antibiotics administered at the same dosage and for the same duration used for the treatment of early, localized Lyme borreliosis in immunocompetent patients. The patients had a smooth course of illness and a favorable outcome but did not ...

Lyme disease is caused by the spirochete Borrelia burgdorferi. Depending on the stage of illness, infection may be limited to the skin or involve the cardiac, nervous and musculoskeletal systems. Herein, we report a case of Lyme disease in a 23-year-old woman from North of Iran (Mazandaran) in early-localized stage of erythema chronicum migrans. The diagnosis was confirmed by the presence of se...